Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12547542 | 0.92 | MET (0.56) | MET | |
| SCHEMBL12547422 | 0.90 | MET (0.56) | MET | |
| SCHEMBL12547718 | 0.88 | MET (0.49) | MET | |
| SCHEMBL12547561 | 0.87 | MET (0.57) | MET | |
| SCHEMBL12547603 | 0.86 | MET (0.58) | MET | |
| SCHEMBL12547797 | 0.86 | MET (0.57) | MET | |
| SCHEMBL12547697 | 0.85 | MET (0.59) | MET | |
| SCHEMBL12547546 | 0.84 | MET (0.64) | MET | |
| SCHEMBL12547853 | 0.84 | MET (0.62) | MET | |
| SCHEMBL19267186 | 0.83 | MET (0.63) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435986-B2 | Bicyclic traizole derivatives for treating of tumors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-07 | — | — | US | disclosed |
| US-8435986-B2 | Bicyclic traizole derivatives for treating of tumors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-07 | — | — | US | disclosed |
| US-20110135600-A1 | BICYCLIC TRAIZOLE DERIVATIVES FOR TREATING OF TUMORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG | 2011-06-09 | — | — | US | disclosed |
| US-20110135600-A1 | BICYCLIC TRAIZOLE DERIVATIVES FOR TREATING OF TUMORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110135600-A1 | BICYCLIC TRAIZOLE DERIVATIVES FOR TREATING OF TUMORS | RET, BMX, ERBB2 | MET 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.