SCHEMBL12554240

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1390743	0.88	CYP3A4 (0.60)	CYP3A4ACHEHPGDSMN1; SMN2TDP1
	SCHEMBL12553846	0.86	GLO1 (0.47)	CYP3A4ACHEHPGDSMN1; SMN2GLO1
	SCHEMBL12587368	0.84	CYP3A4 (0.47)	CYP3A4ACHEHPGDGLO1POLB
	SCHEMBL12586318	0.83	CYP3A4 (0.58)	CYP3A4ACHEHPGDSMN1; SMN2GLO1
	SCHEMBL23484417	0.82	CYP3A4 (0.68)	CYP3A4ACHEHPGDSMN1; SMN2TDP1
	SCHEMBL12586708	0.81	CYP3A4 (0.40)	CYP3A4ACHEHPGDGLO1POLB
	SCHEMBL14363320	0.80	GLO1 (0.43)	CYP3A4ACHEHPGDTDP1GLO1
	SCHEMBL197898	0.79	CYP3A4 (0.81)	CYP3A4ACHEHPGDSMN1; SMN2TDP1
	SCHEMBL23804635	0.78	CYP3A4 (0.45)	CYP3A4HPGDSMN1; SMN2POLBRECQL
	SCHEMBL20681674	0.78	CYP3A4 (0.69)	CYP3A4ACHEHPGDSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.