SCHEMBL12554333

SCHEMBL12554333

CCCCCCCCCCCCCCCCCC(=O)OCC(O)COCCCC

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.69
KDM4E B2RXH2 1/20 0.69
DUSP3 P51452 1/20 0.69
MEN1 O00255 1/20 0.69
KMT2A Q03164 1/20 0.69
ENPP2 Q13822 6/20 0.64
LPAR1 Q92633 6/20 0.64
LPAR4 Q99677 3/20 0.64
LPAR5 Q9H1C0 3/20 0.64
LPAR2 Q9HBW0 3/20 0.64
LPAR3 Q9UBY5 3/20 0.64
LPAR6 P43657 2/20 0.64
MAPT P10636 1/20 0.63
DGKA P23743 2/20 0.58
ALDH1A1 P00352 1/20 0.57
TRPV1 Q8NER1 2/20 0.56
CES2 O00748 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15096661 1.00 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL12554987 1.00 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL19241181 0.97 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL27166293 0.97 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL10477783 0.97 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL25229650 0.97 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL23042348 0.97 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL29362008 0.97 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL19941706 0.95 LMNA (0.71) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL16236223 0.95 LMNA (0.66) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2667947-B1 UV-PHOTO-PROTECTING COSMETIC COMPOSITION MOMENTIVE PERFORMANCE MAT GMBH (DE) 2018-07-25 EP disclosed
EP-2504381-B1 HYDROPHILIC/LIPOPHILIC MODIFIED POLYSILOXANES AS EMULSIFIERS MOMENTIVE PERFORMANCE MAT GMBH (DE) 2018-03-07 EP disclosed
US-9340650-B2 Hydrophilic/lipophilic modified polysiloxanes as emsulsifiers MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2016-05-17 US disclosed
US-9340650-B2 Hydrophilic/lipophilic modified polysiloxanes as emsulsifiers MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2016-05-17 US disclosed
WO-2012170606-A1 CLARIFYING AGENTS FOR ORGANOMODIFIED SILICONES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-12-13 WO disclosed
WO-2011064255-A1 HYDROPHILIC/LIPOPHILIC MODIFIED POLYSILOXANES AS EMULSIFIERS MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2011-06-03 WO disclosed