SCHEMBL125544

SCHEMBL125544

O=C(O)c1cc(Cl)c2c(c1)C(=O)OC2=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 11/20 0.57
TPMT P51580 2/20 0.45
TSHR P16473 2/20 0.41
HCAR1 Q9BXC0 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
POLB P06746 2/20 0.37
CYP3A4 P08684 2/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 2/20 0.37
RECQL P46063 2/20 0.37
KMT2A Q03164 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671367 0.92 TTR (0.50) TTRTPMTTSHRHCAR1CA12
SCHEMBL7727729 0.81 TTR (0.43) TTRCA1CA2CA7MEN1
SCHEMBL9462263 0.80 TTR (0.58) TTRTPMTTSHRHCAR1CA12
SCHEMBL10454988 0.80 MAPT (0.53) TTRTPMTTSHRHCAR1CA12
SCHEMBL31423810 0.80 CA12 (0.43) TTRTPMTTSHRCA12CA1
SCHEMBL3418940 0.80 CA12 (0.43) TTRTPMTTSHRCA12CA1
SCHEMBL309422 0.79 TTR (0.41) TTRTSHRCA12CA1CA2
SCHEMBL8131558 0.79 TTR (0.38) TTRTPMTTSHRCA12CA1
SCHEMBL8174301 0.79 TTR (0.47) TTRTPMTTSHRCA12CA1
SCHEMBL17819141 0.79 PTPRC (0.51) TTRTSHRCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2807 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250176537-A1 POLYESTER-POLYETHER SOLID ARTICLE COMPRISING PHEROMONE THE PROCTER & GAMBLE COMPANY 2025-06-05 US claimed
US-20250177597-A1 POLYESTER-POLYETHER SOLID ARTICLE COMPRISING HYDROPHOBIC MATERIAL THE PROCTER & GAMBLE COMPANY 2025-06-05 US claimed
CN-119931586-A Preparation method of polyamide imide-polyimide copolymer resin adhesive and semiconductor element temporary packaging adhesive film 芜湖徽氏新材料科技有限公司 2025-05-06 CN claimed
CN-118991271-A Preparation method of quantum dot functional printing light guide plate 广东欧迪明光电科技股份有限公司 2024-11-22 CN claimed
WO-2023192255-A9 OPTICALLY TRANSPARENT POLYAMIDE-IMIDES ZYMERGEN INC. (US) 2024-10-24 WO claimed
US-12110390-B2 Solid dispersion, preparation method therefor, chain-extended polyurethane using same, and epoxy resin composition comprising same SAMYANG CORPORATION (KR) 2024-10-08 US claimed
CN-117343601-A Preparation method of friction-resistant anti-decoloration electrochemical aluminum color layer coating 江苏众立生包装科技有限公司 2024-01-05 CN claimed
CN-117210131-A Preparation method of inert polyurethane-alkyd resin gloss oil 江苏众立生包装科技有限公司 2023-12-12 CN claimed
WO-2023192255-A1 OPTICALLY TRANSPARENT POLYAMIDE-IMIDES ZYMERGEN INC. (US) 2023-10-05 WO claimed
CN-116832860-A Preparation method and application of high-molecular supported NHPI and sulfonic acid group bifunctional catalyst 湘潭大学 2023-10-03 CN claimed
EP-0260709-B1 FUSIBLE AND SOLUBLE POLYAMIDEIMIDE-POLYIMIDE BLOCK POLYMERS Chemie Linz Gesellschaft m.b.H. (AT) 1991-07-24 EP claimed
EP-0412731-A1 Improvements in or relating to bakeable aqueous photopolymers Du Pont (UK) Limited (GB) 1991-02-13 EP claimed
EP-0245815-B1 SOLUBLE AND/OR FUSIBLE POLYIMIDES AND POLYAMIDIMIDES Chemie Linz Gesellschaft m.b.H. (AT) 1991-01-02 EP claimed
EP-0371697-A2 Improvements in or relating to polymeric compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-06-06 EP claimed
EP-0368413-A2 Polyphenylene sulfide resin composition GE PLASTICS JAPAN LIMITED (JP) 1990-05-16 EP claimed
US-4886873-A ELASTICITY AND HEAT RESISTANCE DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1989-12-12 US claimed
EP-0260709-A1 Fusible and soluble polyamideimide-polyimide block polymers Chemie Linz Gesellschaft m.b.H. (AT) 1988-03-23 EP claimed
EP-0245815-A2 Soluble and/or fusible polyimides and polyamidimides Chemie Linz Gesellschaft m.b.H. (AT) 1987-11-19 EP claimed
US-4115359-A Crosslinkable polymers prepared from maleimidyl substituted trimellitic acid compounds CIBA-GEIGY CORPORATION (US) 1978-09-19 US claimed
US-3984375-A Aromatic amide-imide polymers WESTINGHOUSE ELECTRIC CORPORATION (US) 1976-10-05 US claimed