SCHEMBL3418940

SCHEMBL3418940

O=C(O)c1cc(C(=O)O)c2c(c1)C(=O)OC2=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.43
CA7 P43166 6/20 0.43
CA1 P00915 5/20 0.43
CA4 P22748 2/20 0.43
TYMS P04818 1/20 0.41
CA2 P00918 3/20 0.40
CA9 Q16790 2/20 0.40
TTR P02766 6/20 0.39
POLB P06746 3/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP3A4 P08684 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
RECQL P46063 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 2/20 0.38
LMNA P02545 1/20 0.38
BCHE P06276 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31423810 1.00 CA12 (0.43) CA12CA7CA1CA4TYMS
SCHEMBL7927900 0.88 CA12 (0.41) CA12CA7CA1CA4TYMS
SCHEMBL6261348 0.88 CA12 (0.38) CA12CA7CA1CA4TYMS
SCHEMBL138029 0.88 CA12 (0.36) CA12CA7CA1CA4TYMS
SCHEMBL10778120 0.83 AKR1C4 (0.46) CA12CA7CA1CA4TYMS
SCHEMBL9462263 0.81 TTR (0.58) CA12CA7CA1CA4TYMS
SCHEMBL10454988 0.81 MAPT (0.53) CA12CA7CA1CA4CA2
SCHEMBL309422 0.80 TTR (0.41) CA12CA7CA1CA4CA2
SCHEMBL8174301 0.80 TTR (0.47) CA12CA7CA1CA4CA2
SCHEMBL17819141 0.80 PTPRC (0.51) CA12CA7CA1CA4TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2148366-B1 Device having plurality of integrated circuits in a matrix COMMISSARIAT ENERGIE ATOMIQUE (FR) 2019-05-01 EP claimed
CN-103864814-B A kind of by the method preparing equal benzene tetramethyl acid anhydride in preparing gasoline by methanol artificial oil 中国海洋石油总公司 2016-06-22 CN claimed
US-20100313752-A1 GAS SEPARATION MEMBRANES AND PROCESSES FOR THE MANUFACTURE THEREOF CO2CRC TECHNOLOGIES PTY LTD (AU) 2010-12-16 US claimed
EP-2215165-A1 GAS SEPARATION MEMBRANES AND PROCESSES FOR THE MANUFACTURE THEREOF CO2CRC Technologies Pty Ltd (AU) 2010-08-11 EP claimed
WO-2009059360-A1 GAS SEPARATION MEMBRANES AND PROCESSES FOR THE MANUFACTURE THEREOF CO2CRC TECHNOLOGIES PTY LTD (AU) 2009-05-14 WO claimed
US-4141926-A Method for preparing epoxy-modified silicon resins SHIN-ETSU CHEMICAL CO., LTD. (JP) 1979-02-27 US claimed
EP-2148366-B1 Device having plurality of integrated circuits in a matrix COMMISSARIAT ENERGIE ATOMIQUE (FR) 2019-05-01 EP disclosed
CN-103864814-B A kind of by the method preparing equal benzene tetramethyl acid anhydride in preparing gasoline by methanol artificial oil 中国海洋石油总公司 2016-06-22 CN disclosed
US-8466568-B2 Multi-component device integrated into a matrix COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2013-06-18 US disclosed
US-20100313752-A1 GAS SEPARATION MEMBRANES AND PROCESSES FOR THE MANUFACTURE THEREOF CO2CRC TECHNOLOGIES PTY LTD (AU) 2010-12-16 US disclosed
EP-2215165-A1 GAS SEPARATION MEMBRANES AND PROCESSES FOR THE MANUFACTURE THEREOF CO2CRC Technologies Pty Ltd (AU) 2010-08-11 EP disclosed
US-20100047567-A1 MULTI-COMPONENT DEVICE INTEGRATED INTO A MATRIX COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2010-02-25 US disclosed
EP-2148366-A1 Device having plurality of integrated circuits in a matrix Commissariat a L'Energie Atomique (FR) 2010-01-27 EP disclosed
WO-2009059360-A1 GAS SEPARATION MEMBRANES AND PROCESSES FOR THE MANUFACTURE THEREOF CO2CRC TECHNOLOGIES PTY LTD (AU) 2009-05-14 WO disclosed
US-4141926-A Method for preparing epoxy-modified silicon resins SHIN-ETSU CHEMICAL CO., LTD. (JP) 1979-02-27 US disclosed