⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoleucine SCHEMBL2783498 | 1.00 | SLC7A5 (0.55) | — | |
| Isoleucine SCHEMBL5973421 | 1.00 | SLC7A5 (0.55) | — | |
| Isoleucine SCHEMBL1255583 | 1.00 | SLC7A5 (0.55) | — | |
| Isoleucine SCHEMBL8043620 | 1.00 | SLC7A5 (0.55) | — | |
| Isoleucine SCHEMBL1255582 | 1.00 | SLC7A5 (0.55) | — | |
| Isoleucine SCHEMBL1147268 | 1.00 | SLC7A5 (0.55) | — | |
| Isoleucine SCHEMBL8045737 | 1.00 | SLC7A5 (0.55) | — | |
| Isoleucine SCHEMBL8868 | 1.00 | — | — | |
| Isoleucine SCHEMBL8186739 | 1.00 | SLC7A5 (0.55) | — | |
| Isoleucine SCHEMBL8869 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854605-A | Method for synthesizing L-allo-isoleucine | 康化（上海）新药研发有限公司 | 2023-10-10 | — | — | CN | claimed |
| EP-4724459-A1 | PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF | Peptidream Inc (JP) | 2026-04-15 | — | — | EP | disclosed |
| EP-4724457-A2 | RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF | Rayzebio, Inc. (US) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024254339-A9 | RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF | RAYZEBIO, INC. (US) | 2025-10-16 | — | — | WO | disclosed |
| WO-2024252336-A1 | PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF | PEPTIDREAM INC. (JP) | 2024-12-12 | — | — | WO | disclosed |
| WO-2024254339-A2 | RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF | RAYZEBIO, INC. (US) | 2024-12-12 | — | — | WO | disclosed |
| US-20240207458-A1 | TARGETED ALPHA PARTICLE THERAPY FOR SOMATOSTATIN RECEPTOR 2 POSITIVE NEUROENDOCRINE TUMORS AND METASTASES | WAKE FOREST UNIVERSITY | 2024-06-27 | — | — | US | disclosed |
| CN-116854605-A | Method for synthesizing L-allo-isoleucine | 康化（上海）新药研发有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116854605-A | Method for synthesizing L-allo-isoleucine | 康化（上海）新药研发有限公司 | 2023-10-10 | — | — | CN | disclosed |
| US-11576946-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | OHIO STATE INNOVATION FOUNDATION (US) | 2023-02-14 | — | — | US | disclosed |
| US-20210169966-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | OHIO STATE INNOVATION FOUNDATION | 2021-06-10 | — | — | US | disclosed |
| US-10010615-B2 | Amino acid conjugates of quetiapine, process for making and using the same | KEMPHARM, INC. (US) | 2018-07-03 | — | — | US | disclosed |