Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14812151 | 0.89 | MAPT (0.47) | MAPTRAB9APOLBTDP1L3MBTL1 | |
| SCHEMBL12563828 | 0.87 | MAPT (0.49) | MAPTRAB9APOLBKDM4EALDH1A1 | |
| SCHEMBL16493139 | 0.86 | MAPT (0.45) | MAPTRAB9AATMPOLBTDP1 | |
| SCHEMBL3421285 | 0.82 | MAPT (0.53) | MAPTRAB9AATMPOLBTDP1 | |
| SCHEMBL12519176 | 0.82 | MAPT (0.53) | MAPTRAB9AATMPOLBTDP1 | |
| SCHEMBL25288186 | 0.82 | MAPT (0.52) | MAPTRAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13252830 | 0.81 | CA12 (0.47) | MAPTRAB9AATMTDP1L3MBTL1 | |
| SCHEMBL1964237 | 0.81 | MAPT (0.75) | MAPTRAB9ATDP1L3MBTL1KDM4E | |
| SCHEMBL1989863 | 0.80 | MAPT (0.54) | MAPTRAB9AATMPOLBTDP1 | |
| SCHEMBL12733610 | 0.80 | MAPT (0.54) | MAPTRAB9AATMPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130022976-A1 | HYPERTHERMOSTABLE ENDONUCLEASE IV SUBSTRATE PROBE | ELITECH HOLDING B.V. | 2013-01-24 | — | — | US | disclosed |
| US-20130022976-A1 | HYPERTHERMOSTABLE ENDONUCLEASE IV SUBSTRATE PROBE | ELITECH HOLDING B.V. | 2013-01-24 | — | — | US | disclosed |
| US-20110151457-A1 | HYPERTHEROMOSTABLE ENDONUCLEASE IV SUBSTRATE PROBE | ELITECH HOLDING B.V. | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110151457-A1 | HYPERTHEROMOSTABLE ENDONUCLEASE IV SUBSTRATE PROBE | DNASE1, FEN1, UNG | MAPT 3951/4885RAB9A 4477/4885ATM 2436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.