Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25288186 | 0.96 | MAPT (0.52) | MAPTRAB9APOLBALDH1A1CYP1A2 | |
| SCHEMBL18105841 | 0.88 | L3MBTL1 (0.55) | MAPTRAB9APOLBALDH1A1KMT2A | |
| SCHEMBL12563864 | 0.87 | MAPT (0.47) | MAPTRAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL12518955 | 0.84 | MAPT (0.54) | MAPTRAB9APOLBALDH1A1CYP1A2 | |
| SCHEMBL29768570 | 0.83 | TCF4 (0.50) | MAPTRAB9APOLBALDH1A1CYP1A2 | |
| SCHEMBL1989028 | 0.82 | KMT2A (0.62) | MAPTRAB9AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL18105809 | 0.82 | LOXL2 (0.52) | MAPTRAB9APOLBALDH1A1MRGPRX4 | |
| SCHEMBL18105808 | 0.82 | LOXL2 (0.52) | MAPTRAB9APOLBALDH1A1MRGPRX4 | |
| SCHEMBL31286940 | 0.82 | RAB9A (0.55) | MAPTRAB9APOLBALDH1A1CYP1A2 | |
| SCHEMBL385706 | 0.81 | RAB9A (0.59) | MAPTRAB9APOLBALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130022976-A1 | HYPERTHERMOSTABLE ENDONUCLEASE IV SUBSTRATE PROBE | ELITECH HOLDING B.V. | 2013-01-24 | — | — | US | disclosed |
| US-20110151457-A1 | HYPERTHEROMOSTABLE ENDONUCLEASE IV SUBSTRATE PROBE | ELITECH HOLDING B.V. | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110151457-A1 | HYPERTHEROMOSTABLE ENDONUCLEASE IV SUBSTRATE PROBE | DNASE1, FEN1, UNG | MAPT 3951/4885RAB9A 4477/4885POLB 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.