Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27694472 | 0.86 | IRAK4 (0.64) | ELANEIRAK4MAPTGAAAKR1C3 | |
| SCHEMBL2228864 | 0.85 | ELANE (0.55) | ELANEIRAK4MAPTGAAAKR1C3 | |
| SCHEMBL7669351 | 0.84 | KDM4E (0.56) | IRAK4MAPTMAPK1KDM4EHSD17B10 | |
| SCHEMBL11402308 | 0.83 | KMT2A (0.60) | ELANEIRAK4MAPTGAAAKR1C3 | |
| Hydrochloric Acid SCHEMBL9114444 | 0.83 | KDM4E (0.54) | IRAK4MAPTMAPK1KDM4EHSD17B10 | |
| Acetic Acid SCHEMBL21549818 | 0.82 | ELANE (0.53) | ELANEIRAK4MAPTGAAAKR1C3 | |
| SCHEMBL31602130 | 0.81 | ELANE (0.54) | ELANEMAPTGAAAKR1C3ABCB1 | |
| SCHEMBL770171 | 0.81 | ELANE (0.54) | ELANEMAPTGAAAKR1C3ABCB1 | |
| SCHEMBL11768273 | 0.81 | IRAK4 (0.77) | IRAK4MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL2588916 | 0.81 | ELANE (0.59) | ELANEMAPTGAAAKR1C3ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178821-A1 | POLYMORPHIC FORM OF TOREMIFENE CITRATE AND PROCESS FOR ITS PREPARATION | RANBAXY LABORATORIES LIMITED (IN) | 2012-07-12 | — | — | US | disclosed |
| EP-2459517-A1 | POLYMORPHIC FORM OF TOREMIFENE CITRATE AND PROCESS FOR ITS PREPARATION | Ranbaxy Laboratories Limited (IN) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011013108-A1 | POLYMORPHIC FORM OF TOREMIFENE CITRATE AND PROCESS FOR ITS PREPARATION | RANBAXY LABORATORIES LIMITED (IN) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178821-A1 | POLYMORPHIC FORM OF TOREMIFENE CITRATE AND PROCESS FOR ITS PREPARATION | CYP19A1, CHRNE, CYP3A5 | ELANE 1341/4885IRAK4 4807/4885MAPT 3238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.