Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GGT1 | P19440 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9114444 | 0.98 | KDM4E (0.54) | KDM4EHSD17B10HPGDIRAK4ALDH1A1 | |
| SCHEMBL11768273 | 0.85 | IRAK4 (0.77) | KDM4EHSD17B10HPGDIRAK4ALDH1A1 | |
| SCHEMBL104892 | 0.85 | IRAK4 (0.70) | KDM4EHSD17B10HPGDIRAK4ALDH1A1 | |
| SCHEMBL10619157 | 0.85 | KDM4E (0.59) | KDM4EHSD17B10HPGDIRAK4ALDH1A1 | |
| SCHEMBL8175115 | 0.85 | KDM4E (0.55) | KDM4EHSD17B10HPGDIRAK4ALDH1A1 | |
| SCHEMBL1256752 | 0.84 | ELANE (0.54) | KDM4EHSD17B10HPGDIRAK4ALDH1A1 | |
| SCHEMBL1134227 | 0.83 | KDM4E (0.58) | KDM4EHSD17B10HPGDIRAK4ALDH1A1 | |
| SCHEMBL10337047 | 0.83 | KDM4E (0.58) | KDM4EHSD17B10HPGDIRAK4ALDH1A1 | |
| Bicarbonate SCHEMBL21811920 | 0.83 | IRAK4 (0.68) | KDM4EHSD17B10HPGDIRAK4ALDH1A1 | |
| SCHEMBL10763308 | 0.83 | IRAK4 (0.68) | KDM4EHSD17B10HPGDIRAK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108003085-A | A kind of synthetic method of pharmaceutical intermediate sweet-smelling formacyl indole derivatives | 张开良 | 2018-05-08 | — | — | CN | disclosed |
| CN-106029654-A | Preparation of 3, 4-dihydro-1, 4-benzoxazepin-5 (2H) -one derivatives by cyclization of 2- (aminoethoxy) benzoic acid derivatives | 吉利德科学公司 | 2016-10-12 | — | — | CN | disclosed |
| US-6380185-B1 | FOR PREVENTION OF OSTEOPOROSIS, BONE LOSS | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-1159268-A1 | N-SUBSTITUTED BENzOYL INDOLES AS ESTROGENIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000051983-A1 | N-SUBSTITUTED BENzOYL INDOLES AS ESTROGENIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |
| US-5475021-A | Administering N-substituted succinimides | VANDERBILT UNIVERSITY (US) | 1995-12-12 | — | — | US | disclosed |
| WO-1995015163-A1 | NOVEL COMPOUNDS FOR INHIBITION OF CYCLOOXYGENASE ACTIVITY | VANDERBILT UNIVERSITY (US) | 1995-06-08 | — | — | WO | disclosed |