Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1257417 | 1.00 | POLB (0.45) | POLBFDPSSLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL700059 | 0.98 | SLC6A2 (0.44) | POLBFDPSSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL5100832 | 0.95 | POLB (0.43) | POLBFDPSSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL5100727 | 0.95 | POLB (0.43) | POLBFDPSSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL5100837 | 0.95 | POLB (0.43) | POLBFDPSSLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL15157362 | 0.93 | POLB (0.42) | POLBFDPSSLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL15157364 | 0.93 | POLB (0.42) | POLBFDPSSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL11116359 | 0.85 | MGAM (0.43) | POLBSLC6A2SLC6A3SLC6A4KMT2A | |
| Trifluoroacetic Acid SCHEMBL10724195 | 0.85 | KCNN4 (0.39) | POLBSLC6A2SLC6A3SLC6A4ABL1 | |
| SCHEMBL24739380 | 0.83 | FDPS (0.41) | POLBFDPSSLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024213044-A1 | AZACYCLO-CARBONYL-FUSED RING DERIVATIVES AND USE THEREOF | Beijing Double-Crane Runchuang Technology Co., Ltd. (CN) | 2024-10-17 | — | — | WO | disclosed |
| CN-115677723-B | 5-HT2A receptor antagonists and their use for treating central nervous system disorders | 瀚远医药有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-115677723-A | 5-HT2A receptor antagonists and their use for the treatment of central nervous system disorders | 瀚远医药有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-113214289-B | 5-HT2A receptor antagonists and their use for the treatment of central nervous system disorders | 瀚远医药有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-113214289-A | 5-HT2A receptor antagonists and their use for the treatment of central nervous system disorders | 瀚远医药有限公司 | 2021-08-06 | — | — | CN | disclosed |
| WO-2021147818-A1 | 5-HT2A RECEPTOR ANTAGONIST AND APPLICATION THEREOF IN TREATING CENTRAL NERVOUS SYSTEM DISEASES | 瀚远医药有限公司 | 2021-07-29 | — | — | WO | disclosed |
| US-9493412-B2 | Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-11-15 | — | — | US | disclosed |
| US-9493412-B2 | Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-11-15 | — | — | US | disclosed |
| US-9493412-B2 | Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-11-15 | — | — | US | disclosed |
| EP-2760830-B1 | PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-08-03 | — | — | EP | disclosed |
| EP-1315495-A2 | USE OF THREO-METHYLPHENIDATE COMPOUNDS TO ENHANCE MEMORY | Sention, Inc. (US) | 2003-06-04 | — | — | EP | disclosed |
| CN-1395575-A | Novel piperidine compounds and drugs containing the same | EISAI CO LTD (JP) | 2003-02-05 | — | — | CN | disclosed |
| WO-2003002561-A1 | N-AROYL CYCLIC AMINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-01-09 | — | — | WO | disclosed |
| EP-1254904-A1 | NOVEL PIPERIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-11-06 | — | — | EP | disclosed |
| WO-2002017919-A2 | USE OF THREO-METHYLPHENIDATE COMPOUNDS TO ENHANCE MEMORY | SENTION, INC. (US) | 2002-03-07 | — | — | WO | disclosed |
| WO-2001058871-A1 | PIPERIDYL CARBOXYLIC ACIDS AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-16 | — | — | WO | disclosed |
| WO-2000071519-A2 | IMMUNOPOTENTIATOR AGENTS | ELI LILLY AND COMPANY (US) | 2000-11-30 | — | — | WO | disclosed |
| US-5552398-A | TREATMENT OF IRRITABLE BOWEL DIARRHEA | SMITHKLINE BEECHAM P.L.C. (GB) | 1996-09-03 | — | — | US | disclosed |
| EP-0603220-A1 | AZABICYCLIC COMPOUNDS AS 5-HT 4? RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993005040-A1 | AZABICYCLIC COMPOUNDS AS 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-03-18 | — | — | WO | disclosed |