Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 5/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467415 | 0.85 | NR2F2 (0.49) | ABL1RIN1NR2F2GALR3 | |
| SCHEMBL13467655 | 0.80 | NPC1 (0.66) | ABL1RIN1NR2F2GALR3ADORA3 | |
| SCHEMBL14713387 | 0.80 | ADORA3 (0.73) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL20626397 | 0.80 | ADORA3 (0.73) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL14713380 | 0.80 | ADORA3 (0.73) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL20626477 | 0.80 | ADORA3 (0.73) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL20626184 | 0.80 | ADORA3 (0.73) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL20626476 | 0.80 | ADORA3 (0.73) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL20626181 | 0.80 | ADORA3 (0.73) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL20626301 | 0.80 | ADORA3 (0.73) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011069294-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | 中国医学科学院药物研究所 (CN) | 2011-06-16 | — | — | WO | disclosed |