Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467240 | 0.89 | HIF1A (0.58) | HIF1ASLC29A1 | |
| SCHEMBL12579937 | 0.85 | HIF1A (0.54) | HIF1ASLC29A1 | |
| SCHEMBL25098371 | 0.84 | HIF1A (0.67) | HIF1ASLC29A1 | |
| SCHEMBL20626254 | 0.84 | ADORA3 (0.73) | HIF1ASLC29A1 | |
| SCHEMBL20626402 | 0.84 | ADORA3 (0.73) | HIF1ASLC29A1 | |
| SCHEMBL14714066 | 0.84 | ADORA3 (0.73) | HIF1ASLC29A1 | |
| SCHEMBL20626165 | 0.84 | ADORA3 (0.73) | HIF1ASLC29A1 | |
| SCHEMBL20626444 | 0.84 | ADORA3 (0.73) | HIF1ASLC29A1 | |
| SCHEMBL20626241 | 0.84 | ADORA3 (0.73) | HIF1ASLC29A1 | |
| SCHEMBL20626445 | 0.84 | ADORA3 (0.73) | HIF1ASLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511283-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011069294-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | 中国医学科学院药物研究所 (CN) | 2011-06-16 | — | — | WO | disclosed |