Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.54 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 5/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.38 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.38 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13352075 | 0.89 | LPAR1 (0.57) | LPAR1LPAR3LPAR2RECQLTLR2 | |
| SCHEMBL12349096 | 0.89 | LPAR1 (0.57) | LPAR1LPAR3LPAR2RECQLTLR2 | |
| SCHEMBL12349100 | 0.87 | LPAR1 (0.57) | LPAR1LPAR3LPAR2RECQLTLR2 | |
| SCHEMBL15166533 | 0.87 | LPAR1 (0.56) | LPAR1LPAR3LPAR2RECQLTLR2 | |
| SCHEMBL12368989 | 0.86 | LPAR1 (0.56) | LPAR1LPAR3LPAR2RECQLTLR2 | |
| SCHEMBL12348908 | 0.85 | LPAR1 (0.51) | LPAR1LPAR3LPAR2RECQLTLR2 | |
| SCHEMBL15166531 | 0.85 | RECQL (0.64) | LPAR1LPAR3LPAR2RECQL | |
| SCHEMBL12348984 | 0.84 | P2RY10 (0.53) | LPAR1LPAR3LPAR2PLA2G2C | |
| SCHEMBL17319478 | 0.83 | RECQL (0.54) | LPAR1LPAR3LPAR2RECQL | |
| SCHEMBL12345721 | 0.81 | LPAR3 (0.82) | LPAR1LPAR3LPAR2RECQLLPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010052718-A9 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-06-16 | — | — | WO | disclosed |