SCHEMBL12348984

SCHEMBL12348984

CCCCCC/C=C/CCCCCCCCOCC(COP(=O)(O)OCCNC)OCCCCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ P2RY10 O00398 6/20 0.53
▸ LPAR1 Q92633 5/20 0.51
▸ LPAR3 Q9UBY5 4/20 0.51
▸ GPR34 Q9UPC5 1/20 0.48
▸ PLA2G2C Q5R387 1/20 0.48
▸ EPHX2 P34913 2/20 0.46
▸ ENPP2 Q13822 1/20 0.46
▸ LPAR2 Q9HBW0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13352075 0.94 LPAR1 (0.57) P2RY10LPAR1LPAR3GPR34PLA2G2C
SCHEMBL12349096 0.94 LPAR1 (0.57) P2RY10LPAR1LPAR3GPR34PLA2G2C
SCHEMBL12349100 0.92 LPAR1 (0.57) P2RY10LPAR1LPAR3PLA2G2CLPAR2
SCHEMBL12345737 0.91 P2RY10 (0.59) P2RY10LPAR1LPAR3GPR34PLA2G2C
SCHEMBL12348908 0.91 LPAR1 (0.51) P2RY10LPAR1LPAR3GPR34PLA2G2C
SCHEMBL10948714 0.86 LPAR3 (0.63) P2RY10LPAR1LPAR3PLA2G2CENPP2
SCHEMBL10948724 0.86 LPAR3 (0.63) P2RY10LPAR1LPAR3PLA2G2CENPP2
SCHEMBL10952127 0.86 LPAR3 (0.63) P2RY10LPAR1LPAR3PLA2G2CENPP2
SCHEMBL10952137 0.86 LPAR3 (0.63) P2RY10LPAR1LPAR3PLA2G2CENPP2
SCHEMBL12345666 0.84 LPAR1 (0.64) P2RY10LPAR1LPAR3GPR34PLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110207703-A1 OXIDIZED LIPID COMPOUNDS AND USES THEREOF VASCULAR BIOGENICS LTD. (IL) 2011-08-25 — — US disclosed
WO-2010052718-A9 OXIDIZED LIPID COMPOUNDS AND USES THEREOF VASCULAR BIOGENICS LTD. (IL) 2011-06-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110207703-A1 OXIDIZED LIPID COMPOUNDS AND USES THEREOF LPO, GPX4, ALOX15B P2RY10 1977/4885LPAR1 305/4885LPAR3 417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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