SCHEMBL12588602

SCHEMBL12588602

C[SiH](C)O[SiH](C)O[Si](C)(O[SiH](C)C)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19491565 0.89
SCHEMBL297373 0.88 ESR1 (0.37) ESR1ESR2
SCHEMBL14826773 0.87
SCHEMBL14156502 0.85 ESR1 (0.32) ESR1ESR2
SCHEMBL17704579 0.84
SCHEMBL15483444 0.83
SCHEMBL17704577 0.81 ESR1 (0.32) ESR1ESR2
SCHEMBL11911704 0.80 ESR1 (0.34) ESR1ESR2
SCHEMBL14286506 0.79
SCHEMBL11911720 0.79 ESR1 (0.33) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11692067-B2 Polysilocarb materials, methods and uses MELIOR INNOVATIONS, INC. (US) 2023-07-04 US disclosed
US-9884961-B2 Phosphazene flame retardant polycarbonate compounds POLYONE CORPORATION (US) 2018-02-06 US disclosed
US-20160272812-A1 PHOSPHAZENE FLAME RETARDANT POLYCARBONATE COMPOUNDS POLYONE CORPORATION (US) 2016-09-22 US disclosed
US-20160122534-A1 COMPLETELY NON-HALOGENATED FLAME RETARDANT POLYCARBONATE COMPOUNDS POLYONE CORPORATION (US) 2016-05-05 US disclosed
US-20160046529-A1 Polymer Derived Ceramic Equipment for the Exploration and Recovery of Resources MELIOR INNOVATIONS, INC. (US) 2016-02-18 US disclosed
US-20150175750-A1 POLYSILOCARB MATERIALS, METHODS AND USES MELIOR INNOVATIONS, INC. (US) 2015-06-25 US disclosed
US-8865029-B2 Photochromic polymer and composition comprising photochromic polymer Vivimed Labs Europe Ltd. (GB) 2014-10-21 US disclosed
US-8440776-B2 Lens-forming silicone resin composition and silicone lens SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-05-14 US disclosed
US-20110147681-A1 Photochromic Polymer and Composition Comprising Photochromic Polymer ADVANCED POLYMERIK PTY LTD (AU) 2011-06-23 US disclosed
US-7830081-B2 Optoelectronic devices with multilayered structures GENERAL ELECTRIC COMPANY (US) 2010-11-09 US disclosed
US-20100197870-A1 LENS-FORMING SILICONE RESIN COMPOSITION AND SILICONE LENS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-08-05 US disclosed
US-7633220-B2 Optoelectronic devices with multilayered structures GENERAL ELECTRIC COMPANY (US) 2009-12-15 US disclosed
US-20090105395-A1 CURABLE RESIN COMPOSITION ENIKOLOPOV INST OF SYNTH POLY (RU) 2009-04-23 US disclosed
US-20070225464-A1 OPTOELECTRONIC DEVICES WITH MULTILAYERED STRUCTURES GENERAL ELECTRIC COMPANY (US) 2007-09-27 US disclosed
US-20070225454-A1 OPTOELECTRONIC DEVICES WITH MULTILAYERED STRUCTURES GENERAL ELECTRIC COMPANY (US) 2007-09-27 US disclosed
US-20070225477-A1 OPTOELECTRONIC DEVICES WITH MULTILAYERED STRUCTURES GENERAL ELECTRIC COMPANY (US) 2007-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110147681-A1 Photochromic Polymer and Composition Comprising Photochromic Polymer SMCHD1, PCNA, PARG ESR1 3068/4885ESR2 3362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.