SCHEMBL14156502

SCHEMBL14156502

C[SiH](O[SiH](C)O[Si](C)(O[SiH](C)O[SiH](C)O[Si](C)(C)C)c1ccccc1)O[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12588602 0.85 ESR1 (0.31) ESR1ESR2
SCHEMBL9007127 0.85 ESR1 (0.31) ESR1ESR2
SCHEMBL12680911 0.81
SCHEMBL9007146 0.80
SCHEMBL14826773 0.79
SCHEMBL297373 0.79 ESR1 (0.37) ESR1ESR2
SCHEMBL12023366 0.78
SCHEMBL19491565 0.78
SCHEMBL15950073 0.78 ESR1 (0.33) ESR1ESR2
SCHEMBL25772720 0.78 ESR1 (0.33) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7390349-B2 Polyhydrosiloxane compounds and articles and use thereof AGILENT TECHNOLOGIES, INC. (US) 2008-06-24 US disclosed