SCHEMBL12588679

SCHEMBL12588679

C=CC=COCCCOc1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.37
L3MBTL1 Q9Y468 4/20 0.37
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
HPGD P15428 2/20 0.34
MAPK1 P28482 1/20 0.34
KDM4E B2RXH2 1/20 0.33
S1PR4 O95977 1/20 0.32
ORAI1 Q96D31 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
PLAU P00749 1/20 0.31
CYP1A2 P05177 1/20 0.31
S1PR2 O95136 1/20 0.30
S1PR1 P21453 1/20 0.30
S1PR3 Q99500 1/20 0.30
LPAR2 Q9HBW0 1/20 0.30
POLB P06746 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12588681 0.77 MAPT (0.37) MAPTL3MBTL1ALDH1A1TDP1HPGD
SCHEMBL3886565 0.74 MAPT (0.44) MAPTL3MBTL1ALDH1A1TDP1HPGD
SCHEMBL29054688 0.72 MAPT (0.42) MAPTL3MBTL1ALDH1A1TDP1HPGD
SCHEMBL12670376 0.71 PTGDR (0.41) MAPTL3MBTL1ALDH1A1TDP1KDM4E
SCHEMBL28294654 0.70
SCHEMBL3804284 0.70 TSHR (0.50) MAPTL3MBTL1ALDH1A1TDP1HPGD
SCHEMBL8408841 0.70 MAPT (0.42) MAPTL3MBTL1ALDH1A1TDP1HPGD
SCHEMBL8920540 0.69 MAPT (0.45) MAPTL3MBTL1ALDH1A1TDP1HPGD
SCHEMBL12588685 0.68 KCNA3 (0.52) ALDH1A1KDM4ESMN1; SMN2
SCHEMBL4427150 0.68 PTGDR (0.41) MAPTL3MBTL1ALDH1A1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110129636-A1 Block Copolymer Containing a Photoactive Monomer Bearing a Photoisomerizable Group, Use Thereof in a 3D Optical Memory ARKEMA FRANCE (FR) 2011-06-02 US disclosed
US-20100119761-A1 OPTICAL 3D MEMORY COMPRISING A BLOCK COPOLYMER CONTAINING A PHOTOACTIVE MONOMER HAVING A PHOTOISOMERABLE GROUP ARKEMA FRANCE (FR) 2010-05-13 US disclosed
US-20090321694-A1 Optical 3D memory comprising multilayer particles that comprise a photoactive monomer bearing a photoisomerizable group ARKEMA FRANCE (FR) 2009-12-31 US disclosed