Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076447 | 0.83 | HPGD (0.41) | MAPTTDP1PLAUL3MBTL1KDM4E | |
| SCHEMBL1764470 | 0.81 | CA1 (0.40) | MAPTTDP1PLAUL3MBTL1SMN1; SMN2 | |
| SCHEMBL9348258 | 0.79 | MAPT (0.46) | MAPTTDP1PLAUL3MBTL1SMN1; SMN2 | |
| SCHEMBL9349699 | 0.77 | MAPT (0.45) | MAPTTDP1PLAUL3MBTL1SMN1; SMN2 | |
| SCHEMBL13261204 | 0.77 | MAPT (0.49) | MAPTTDP1PLAUL3MBTL1SMN1; SMN2 | |
| SCHEMBL9622239 | 0.77 | PLAU (0.61) | MAPTTDP1PLAUL3MBTL1SMN1; SMN2 | |
| SCHEMBL9324460 | 0.77 | MAPT (0.45) | MAPTTDP1PLAUL3MBTL1SMN1; SMN2 | |
| SCHEMBL6474960 | 0.77 | KMT2A (0.48) | MAPTL3MBTL1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL29054688 | 0.77 | MAPT (0.42) | MAPTTDP1PLAUL3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10442699 | 0.76 | PLAU (0.59) | MAPTTDP1PLAUL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159584-B1 | N-(AZOLYLCARBAMOYL)-HYDROXYL AMINES AND FUNGICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1989-01-18 | — | — | EP | claimed |
| US-5591751-A | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0636128-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| WO-1994019339-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |