⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15779623 | 1.00 | — | — | |
| SCHEMBL24473443 | 1.00 | — | — | |
| SCHEMBL31717069 | 0.84 | — | — | |
| SCHEMBL805249 | 0.82 | — | — | |
| SCHEMBL2980803 | 0.82 | — | — | |
| SCHEMBL13227766 | 0.82 | — | — | |
| SCHEMBL13494846 | 0.80 | MMP2 (0.37) | — | |
| SCHEMBL27072471 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL2519313 | 0.80 | GRIK1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL2523807 | 0.80 | GRIK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-18 | — | — | US | disclosed |
| EP-3225627-A1 | TRIPEPTIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Northwest University (CN) | 2017-10-04 | — | — | EP | disclosed |
| US-20170267718-A1 | TRIPEPTIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | NORTHWEST UNIVERSITY (CN) | 2017-09-21 | — | — | US | disclosed |
| US-20170174750-A1 | Peptide Inhibitors of BCR-ABL Oligomerization | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2017-06-22 | — | — | US | disclosed |
| WO-2015148620-A2 | PEPTIDE INHIBITORS OF BCR-ABL OLIGOMERIZATION | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2015-10-01 | — | — | WO | disclosed |
| US-20110144306-A1 | LIGATION OF STAPLED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-06-16 | — | — | US | disclosed |