Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | TNKS2 | Q9H2K2 | 8/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27944858 | 1.00 | KDM4E (0.65) | KDM4EKMT2AGAAMAPTMEN1 | |
| SCHEMBL28357584 | 0.84 | ALDH1A1 (0.72) | KDM4EKMT2AGAAMAPTMEN1 | |
| SCHEMBL28837986 | 0.76 | TNKS2 (0.66) | KDM4EKMT2AGAAMAPTMEN1 | |
| SCHEMBL13876845 | 0.74 | TNKS2 (0.66) | KDM4EKMT2AGAAMAPTMEN1 | |
| SCHEMBL31103383 | 0.74 | TNKS2 (1.00) | KDM4EKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL24743516 | 0.74 | TNKS2 (1.00) | KDM4EKMT2AGAAHTTALDH1A1 | |
| SCHEMBL6124228 | 0.74 | TNKS2 (0.71) | KDM4EKMT2AGAAMAPTMEN1 | |
| SCHEMBL31338439 | 0.74 | TNKS2 (0.66) | KDM4EKMT2AGAAMAPTMEN1 | |
| SCHEMBL31338437 | 0.74 | TNKS2 (0.66) | KDM4EKMT2AGAAMAPTMEN1 | |
| SCHEMBL4090554 | 0.74 | TNKS2 (0.66) | KDM4EKMT2AGAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103420921-A | Method for synthesizing optically-active 2,3-dihydro quinazolinone derivative by using chiral spiro phosphoric acid as catalyst | UNIV ZHEJIANG | 2013-12-04 | — | — | CN | disclosed |
| US-20110117659-A1 | QUINAZOLINE-CONTAINING KITS FOR LABELING ALDEHYDE OR KETONE MOIETIES | Life Technologies Corporation (US) | 2011-05-19 | — | — | US | disclosed |
| US-20110117659-A1 | QUINAZOLINE-CONTAINING KITS FOR LABELING ALDEHYDE OR KETONE MOIETIES | Life Technologies Corporation (US) | 2011-05-19 | — | — | US | disclosed |
| US-7816527-B2 | Quinazoline-containing kits for labeling aldehyde or ketone moieties | Life Technologies Corporation (US) | 2010-10-19 | — | — | US | disclosed |
| US-7816527-B2 | Quinazoline-containing kits for labeling aldehyde or ketone moieties | Life Technologies Corporation (US) | 2010-10-19 | — | — | US | disclosed |