Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12592535 | 0.92 | CTSD (0.71) | CTSDBACE1 | |
| SCHEMBL12592195 | 0.91 | CTSD (0.70) | CTSDBACE1 | |
| SCHEMBL12592151 | 0.91 | CTSD (0.67) | CTSDBACE1 | |
| SCHEMBL12592788 | 0.91 | CTSD (0.75) | CTSDBACE1 | |
| SCHEMBL25916193 | 0.91 | CTSD (0.75) | CTSDBACE1 | |
| SCHEMBL12592114 | 0.89 | BACE1 (0.66) | CTSDBACE1 | |
| SCHEMBL12591968 | 0.88 | CTSD (0.68) | CTSDBACE1 | |
| SCHEMBL12592202 | 0.87 | CTSD (0.64) | CTSDBACE1 | |
| SCHEMBL12591975 | 0.87 | CTSD (0.68) | CTSDBACE1 | |
| SCHEMBL12592004 | 0.86 | CTSD (0.75) | CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072064-A1 | S PIRO [CHROMAN - 4, 4 ' - IMIDAZOL] ONES AS BETA - SECRETASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2011-06-16 | — | — | WO | disclosed |