Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30211243 | 1.00 | CYP2A6 (0.56) | CYP2A6SQORTRPV1CNR2MAPK14 | |
| SCHEMBL2477267 | 0.83 | TRPV1 (0.62) | CYP2A6TRPV1CNR2NPC1RAB9A | |
| SCHEMBL19248538 | 0.82 | CYP2A6 (0.55) | CYP2A6SQORTRPV1CNR2METAP2 | |
| SCHEMBL13834139 | 0.82 | CYP2A6 (0.63) | CYP2A6TRPV1CNR2METAP2 | |
| SCHEMBL64623 | 0.81 | CYP2A6 (0.68) | CYP2A6TRPV1CNR2RAB9AMEN1 | |
| SCHEMBL32509667 | 0.81 | CYP2A6 (0.68) | CYP2A6TRPV1CNR2RAB9AMEN1 | |
| SCHEMBL10094698 | 0.80 | TRPV1 (0.64) | CYP2A6TRPV1CNR2NPC1RAB9A | |
| SCHEMBL7068186 | 0.80 | CYP2A6 (0.56) | CYP2A6TRPV1CNR2NPC1RAB9A | |
| SCHEMBL3975427 | 0.80 | CYP2A6 (0.56) | CYP2A6SQORTRPV1CNR2NPC1 | |
| SCHEMBL3974637 | 0.80 | CYP2A6 (0.56) | CYP2A6TRPV1CNR2KMT2AMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210179649-A1 | ORGANIC METAL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2021-06-17 | — | — | US | disclosed |
| US-20160031868-A1 | BENZIMIDAZOLONE DERIVATIVES AS BROMODOMAIN INHIBITORS | GILEAD SCIENCES, INC. | 2016-02-04 | — | — | US | disclosed |
| US-20140296246-A1 | BENZIMIDAZOLONE DERIVATIVES AS BROMODOMAIN INHIBITORS | GILEAD SCIENCES, INC. (US) | 2014-10-02 | — | — | US | disclosed |
| WO-2014160873-A1 | BENZIMIDAZOLONE DERIVATIVES AS BROMODOMAIN INHIBITORS | GILEAD SCIENCES, INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-8445509-B2 | Fused heterocyclic derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-05-21 | — | — | US | disclosed |
| US-20110046169-A1 | FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-02-24 | — | — | US | disclosed |
| CN-1989125-B | 2-(pyridin-2-yl)-pyrimidines and their use for controlling pathogenic fungi | BASF AG | 2010-12-01 | — | — | CN | disclosed |
| US-20100286175-A1 | 2-(Pyridin-2-yl)-pyrimidines and Their Use for Controlling Harmful Fungi | GRAMMENOS WASSILIOS | 2010-11-11 | — | — | US | disclosed |
| US-7786043-B2 | 2-(pyridin-2-yl)-pyrimidines and their use for controlling harmful fungi | BASF AKTIENGESELLSCHAFT (DE) | 2010-08-31 | — | — | US | disclosed |
| EP-2172467-A1 | 2-(pyridin -2-yl)-pyrimidines and their use for controlling pathogenic fungi | BASF SE (DE) | 2010-04-07 | — | — | EP | disclosed |
| EP-2172465-A1 | 2-(pyridin -2-yl)-pyrimidines and their use for controlling pathogenic fungi | BASF SE (DE) | 2010-04-07 | — | — | EP | disclosed |
| EP-2172466-A1 | 2-(pyridin-2-yl)-pyrimidines and use of same to combat hazardous fungi | BASF SE (DE) | 2010-04-07 | — | — | EP | disclosed |
| EP-1773806-B1 | 2-(PYRIDIN-2-YL)-PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2010-02-24 | — | — | EP | disclosed |
| WO-2009136663-A1 | FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-12 | — | — | WO | disclosed |
| US-20080027085-A1 | 2-(Pyridin-2-Yl)-Pyrimidines and Their Use for Controlling Harmful Fungi | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-31 | — | — | US | disclosed |
| CN-1989125-A | 2-(pyridin-2-yl)-pyrimidines and their use for controlling pathogenic fungi | BASF AG (DE) | 2007-06-27 | — | — | CN | disclosed |
| EP-1773806-A1 | 2-(PYRIDIN-2-YL)-PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006010570-A1 | 2-(PYRIDIN-2-YL)-PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027085-A1 | 2-(Pyridin-2-Yl)-Pyrimidines and Their Use for Controlling Harmful Fungi | CBR1, CBR3, CNPY2 | CYP2A6 730/4885SQOR 726/4885TRPV1 4227/4885 |
| US-20160031868-A1 | BENZIMIDAZOLONE DERIVATIVES AS BROMODOMAIN INHIBITORS | BRD4, BRD3, BRD1 | CYP2A6 4241/4885SQOR 3790/4885TRPV1 3300/4885 |
| US-20110046169-A1 | FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF | ABL1, MAP4K2, MAP3K20 | CYP2A6 4086/4885SQOR 1238/4885TRPV1 1784/4885 |
| US-20210179649-A1 | ORGANIC METAL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | MRPL38, L1CAM, IL18 | CYP2A6 1420/4885SQOR 995/4885TRPV1 862/4885 |
| US-20100286175-A1 | 2-(Pyridin-2-yl)-pyrimidines and Their Use for Controlling Harmful Fungi | CBR1, CBR3, CNPY2 | CYP2A6 722/4885SQOR 1114/4885TRPV1 4153/4885 |
| US-20140296246-A1 | BENZIMIDAZOLONE DERIVATIVES AS BROMODOMAIN INHIBITORS | BRD4, BRD3, BRD1 | CYP2A6 4241/4885SQOR 3790/4885TRPV1 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.