Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.69 |
| ▸ | FAAH | O00519 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | F7 | P08709 | 3/20 | 0.56 |
| ▸ | F3 | P13726 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | PPARD | Q03181 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | FABP3 | P05413 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | FABP4 | P15090 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533680 | 1.00 | EPHX2 (0.69) | EPHX2FAAHALDH1A1KDM4EF7 | |
| SCHEMBL2637148 | 1.00 | EPHX2 (0.69) | EPHX2FAAHALDH1A1KDM4EF7 | |
| SCHEMBL3458829 | 1.00 | EPHX2 (0.69) | EPHX2FAAHALDH1A1KDM4EF7 | |
| SCHEMBL2637146 | 1.00 | EPHX2 (0.69) | EPHX2FAAHALDH1A1KDM4EF7 | |
| SCHEMBL8985935 | 1.00 | EPHX2 (0.69) | EPHX2FAAHALDH1A1KDM4EF7 | |
| SCHEMBL8985933 | 1.00 | EPHX2 (0.69) | EPHX2FAAHALDH1A1KDM4EF7 | |
| SCHEMBL11370740 | 0.94 | EPHX2 (0.75) | EPHX2FAAHF7F3PPARG | |
| SCHEMBL2219389 | 0.94 | EPHX2 (0.75) | EPHX2FAAHF7F3PPARG | |
| SCHEMBL8349583 | 0.94 | EPHX2 (0.75) | EPHX2FAAHF7F3PPARG | |
| SCHEMBL1962429 | 0.94 | EPHX2 (0.75) | EPHX2FAAHF7F3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092739-A1 | Lipid Nanoparticle Based Compositions and Methods for the Delivery of Biologically Active Molecules | SIMA THERAPEUTICS, INC. (US) | 2011-04-21 | — | — | US | disclosed |
| US-7893302-B2 | novel cationic lipids based on 4-(aminomethyl)-1,2-bis-(fatty ether or ester)-benzene | SIRNA THERAPEUTICS, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-20100048888-A1 | Lipid Nanoparticle Based Compositions and Methods for the Delivery of Biologically Active Molecules | SIRNA THERAPEUTICS, INC., A WHOLLY OWNED SUBSIDIARY OF MERCK & CO., INC. | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092739-A1 | Lipid Nanoparticle Based Compositions and Methods for the Delivery of Biologically Active Molecules | PHAX, CETP, LIPC | EPHX2 873/4885FAAH 1624/4885ALDH1A1 3283/4885 |
| US-20100048888-A1 | Lipid Nanoparticle Based Compositions and Methods for the Delivery of Biologically Active Molecules | PHAX, CETP, LIPC | EPHX2 929/4885FAAH 1505/4885ALDH1A1 3348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.