Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 17/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12593602 | 0.87 | CYP2C9 (0.56) | CCR2CYP2C9CYP3A4 | |
| SCHEMBL12648765 | 0.84 | CYP2C9 (0.55) | CCR2CYP2C9CYP3A4 | |
| SCHEMBL306174 | 0.82 | CYP2C9 (0.65) | CCR2CYP2C9CYP3A4 | |
| SCHEMBL10223170 | 0.81 | CYP2C9 (0.62) | CCR2CYP2C9CYP3A4 | |
| SCHEMBL10222759 | 0.80 | CYP2C9 (0.61) | CCR2CYP2C9CYP3A4 | |
| SCHEMBL306540 | 0.80 | CYP2C9 (0.61) | CCR2CYP2C9CYP3A4 | |
| SCHEMBL307486 | 0.80 | CYP2C9 (0.63) | CCR2CYP2C9CYP3A4 | |
| SCHEMBL10223171 | 0.80 | CYP2C9 (0.63) | CCR2CYP2C9CYP3A4 | |
| SCHEMBL12161484 | 0.80 | CYP2C9 (0.58) | CCR2CYP2C9CYP3A4 | |
| SCHEMBL305922 | 0.80 | CYP2C9 (0.61) | CCR2CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118248-A1 | Heteroaryl sulfonamides and CCR2/CCR9 | CHEMOCENTRYX, INC. | 2011-05-19 | — | — | US | disclosed |
| US-20110118248-A1 | Heteroaryl sulfonamides and CCR2/CCR9 | CHEMOCENTRYX, INC. | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118248-A1 | Heteroaryl sulfonamides and CCR2/CCR9 | CCR2, CCR9, CCR1 | CCR2 1/4885CYP2C9 192/4885CYP3A4 1934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.