Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923833 | 1.00 | OPRD1 (0.34) | OPRD1MAPTPPARGPSMB5 | |
| SCHEMBL6924256 | 1.00 | OPRD1 (0.34) | OPRD1MAPTPPARGPSMB5 | |
| SCHEMBL1173092 | 1.00 | OPRD1 (0.34) | OPRD1MAPTPPARGPSMB5 | |
| SCHEMBL11993565 | 1.00 | OPRD1 (0.34) | OPRD1MAPTPPARGPSMB5 | |
| SCHEMBL1173294 | 1.00 | OPRD1 (0.34) | OPRD1MAPTPPARGPSMB5 | |
| SCHEMBL1173683 | 0.84 | OPRD1 (0.34) | OPRD1 | |
| SCHEMBL1172975 | 0.84 | OPRD1 (0.34) | OPRD1 | |
| SCHEMBL1173512 | 0.81 | BACE1 (0.34) | — | |
| SCHEMBL11993564 | 0.81 | BACE1 (0.37) | — | |
| SCHEMBL1173202 | 0.81 | BACE1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467368-A1 | 3-AMINO-5-PHENYL-5,6-DIHYDRO-2H-[1,4]OXAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-06-27 | — | — | EP | disclosed |
| WO-2011020806-A1 | 3-AMINO-5-PHENYL-5,6-DIHYDRO-2H-[1,4]OXAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-02-24 | — | — | WO | disclosed |