Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.46 |
| ▸ | ESR1 | P03372 | 6/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119237 | 0.88 | ESR1 (0.47) | ESR2ESR1PTPN1MEN1KMT2A | |
| SCHEMBL13665499 | 0.88 | MEN1 (0.39) | ESR2ESR1PTPN1MEN1KMT2A | |
| SCHEMBL1119294 | 0.86 | ESR2 (0.53) | ESR2ESR1PTPN1MEN1KMT2A | |
| SCHEMBL1119209 | 0.83 | ESR1 (0.38) | ESR2ESR1PTPN1MEN1KMT2A | |
| SCHEMBL13665183 | 0.82 | HSD17B10 (0.42) | ESR2ESR1PTPN1MEN1KMT2A | |
| SCHEMBL1119204 | 0.81 | ESR1 (0.46) | ESR2ESR1MEN1KMT2AHSP90AA1 | |
| SCHEMBL1119216 | 0.81 | ESR2 (0.46) | ESR2ESR1MEN1KMT2AHSP90AA1 | |
| SCHEMBL1119210 | 0.78 | ESR2 (0.50) | ESR2ESR1MEN1KMT2AHSP90AA1 | |
| SCHEMBL1119212 | 0.77 | MEN1 (0.39) | ESR2ESR1PTPN1MEN1KMT2A | |
| SCHEMBL1119196 | 0.77 | ESR1 (0.47) | ESR2ESR1MEN1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112142-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-05-12 | — | — | US | disclosed |
| US-20110112142-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112142-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | ESR2, ESR1, ESRRA | ESR2 1/4885ESR1 2/4885PTPN1 938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.