Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119204 | 0.84 | ESR1 (0.46) | HSD17B10ALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL1119216 | 0.84 | ESR2 (0.46) | HSD17B10ALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL13665499 | 0.83 | MEN1 (0.39) | HSD17B10ALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL12596035 | 0.82 | ESR2 (0.46) | HSD17B10ALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL1119210 | 0.82 | ESR2 (0.50) | HSD17B10ALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL1119196 | 0.81 | ESR1 (0.47) | HSD17B10ALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL1119239 | 0.81 | ESR1 (0.49) | HSD17B10ALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL1119237 | 0.81 | ESR1 (0.47) | HSD17B10ALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL1119212 | 0.81 | MEN1 (0.39) | HSD17B10ALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL1119258 | 0.81 | MEN1 (0.39) | HSD17B10ALOX15ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009124968-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2009-10-15 | — | — | WO | disclosed |