Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | TPMT | P51580 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907576 | 0.83 | TPMT (0.56) | MEN1KMT2ATPMTCYP3A4CYP1A2 | |
| SCHEMBL668540 | 0.83 | CA12 (0.69) | RXFP1MEN1KMT2ACA12CA1 | |
| SCHEMBL12327904 | 0.78 | LMNA (0.69) | RXFP1MEN1KMT2ACA12CA1 | |
| SCHEMBL10824650 | 0.78 | MEN1 (0.58) | RXFP1MEN1KMT2ACA12CA1 | |
| SCHEMBL339242 | 0.78 | CA12 (0.71) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL668639 | 0.77 | RXFP1 (0.56) | RXFP1MEN1KMT2ACA12CA1 | |
| SCHEMBL2114318 | 0.77 | KMT2A (0.61) | RXFP1MEN1KMT2ACA12CA1 | |
| SCHEMBL1004561 | 0.77 | TSHR (0.59) | RXFP1MEN1KMT2ACA12CA1 | |
| SCHEMBL5240901 | 0.77 | MEN1 (0.56) | RXFP1MEN1KMT2ACA12CA1 | |
| SCHEMBL27468173 | 0.76 | CA12 (0.69) | MEN1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326834-B1 | 2-SUBSTITUTED HETEROCYCLIC COMPOUNDS | H LEE MOFFITT CANCER CT & RES (US) | 2011-06-29 | — | — | EP | disclosed |