SCHEMBL12599338

SCHEMBL12599338

Cc1cc(C(=O)Oc2ccc(N3C(=O)C4C5C=CC(C5)C4C3=O)cc2)cc(C)c1C

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.61
TSHR P16473 2/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C19 P33261 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
ALDH1A1 P00352 2/20 0.51
CA1 P00915 5/20 0.51
CA2 P00918 5/20 0.51
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13477975 0.86 KMT2A (0.67) KMT2AALDH1A1CA1CA2
SCHEMBL12599306 0.86 KMT2A (0.60) KMT2ATSHRCYP3A4CYP2C19NPSR1
SCHEMBL12599307 0.85 KMT2A (0.59) KMT2ATSHRCYP3A4CYP2C19NPSR1
SCHEMBL3192700 0.83 KMT2A (0.62) KMT2AALDH1A1CA1CA2MEN1
SCHEMBL13477974 0.83 KMT2A (0.62) KMT2AALDH1A1CA1CA2
SCHEMBL12649442 0.82 KMT2A (0.59) KMT2ATSHRCYP3A4CYP2C19NPSR1
SCHEMBL12282274 0.81 CA1 (0.56) KMT2ATSHRCYP3A4CYP2C19NPSR1
SCHEMBL13133138 0.80 KMT2A (0.76) KMT2ATSHRCYP3A4CYP2C19NPSR1
SCHEMBL13337808 0.80 CA1 (0.62) KMT2AALDH1A1CA1CA2MEN1
SCHEMBL12268555 0.80 CA1 (0.66) KMT2AALDH1A1CA1CA2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420287-B2 Positive photosensitive resin composition CHEIL INDUSTRIES INC. (KR) 2013-04-16 US disclosed
US-20110111346-A1 Positive Photosensitive Resin Composition CHEIL INDUSTRIES INC. (KR) 2011-05-12 US disclosed