Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PHPT1 | Q9NRX4 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127374 | 0.83 | HDAC1 (0.47) | HDAC1HDAC3HDAC2NPC1POLB | |
| SCHEMBL2128654 | 0.81 | SMN1; SMN2 (0.54) | HDAC1HDAC3HDAC2NPC1POLB | |
| SCHEMBL5179041 | 0.80 | POLB (0.65) | HDAC1NPC1POLBMAPTRAB9A | |
| SCHEMBL20051328 | 0.78 | HDAC1 (0.49) | HDAC1HDAC3HDAC2NPC1POLB | |
| SCHEMBL29904715 | 0.78 | HDAC1 (0.49) | HDAC1HDAC3HDAC2NPC1POLB | |
| SCHEMBL1143315 | 0.78 | HDAC1 (0.49) | HDAC1HDAC3HDAC2NPC1POLB | |
| SCHEMBL30961638 | 0.78 | HDAC1 (0.49) | HDAC1HDAC3HDAC2NPC1POLB | |
| SCHEMBL8021721 | 0.77 | CA1 (0.51) | HDAC1HDAC3HDAC2NPC1POLB | |
| SCHEMBL6811137 | 0.77 | POLB (0.49) | HDAC1HDAC3HDAC2NPC1POLB | |
| SCHEMBL4059231 | 0.76 | NPC1 (0.55) | HDAC1HDAC3HDAC2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3096735-A1 | GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME | Combe International Ltd. (US) | 2016-11-30 | — | — | EP | claimed |
| WO-2015112789-A1 | GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME | COMBE INTERNATIONAL LTD. (US) | 2015-07-30 | — | — | WO | claimed |
| EP-1129688-B1 | Hair coloring composition using an inorganic peroxymonosulfate salt as an oxidation agent. | P & G CLAIROL INC (US) | 2006-09-27 | — | — | EP | claimed |
| US-7066968-B2 | Efficient two-step method of coloring and lightening hair with less damage | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2006-06-27 | — | — | US | claimed |
| EP-1251822-A4 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P & G CLAIROL INC (US) | 2006-05-31 | — | — | EP | claimed |
| US-7041142-B2 | Two step hair coloring compositions delivering deeper, long-lasting color | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2006-05-09 | — | — | US | claimed |
| US-20060075580-A1 | TWO STEP HAIR COLORING COMPOSITIONS DELIVERING DEEPER, LONG-LASTING COLOR | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2006-04-13 | — | — | US | claimed |
| CN-1681470-A | Agent for dyeing keratinous fibres | HENKEL KGAA (DE) | 2005-10-12 | — | — | CN | claimed |
| US-20050193501-A1 | Efficient two-step method of coloring and lightening hair with less damage | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2005-09-08 | — | — | US | claimed |
| CN-1196464-C | Novel couplers for oxidative hair dyeing | P & G CLAROR INC (US) | 2005-04-13 | — | — | CN | claimed |
| WO-2003055458-A1 | GRADUAL PERMANENT COLORING OF HAIR USING DYE INTERMEDIATES IN A SHAMPOO BASE | UNILEVER PLC (GB) | 2003-07-10 | — | — | WO | claimed |
| US-20030074748-A1 | Method and composition for the gradual permanent coloring of hair | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-04-24 | — | — | US | claimed |
| US-6540793-B1 | Coupler for use in oxidative hair dyeing | CLAIROL INCORPORATED | 2003-04-01 | — | — | US | claimed |
| CN-1396819-A | Novel couplers for oxidative hair dyeing | P & G CLAROR INC (US) | 2003-02-12 | — | — | CN | claimed |
| EP-1251822-A1 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | Clairol Incorporated (US) | 2002-10-30 | — | — | EP | claimed |
| WO-2002074266-A2 | METHOD AND COMPOSITION FOR THE GRADUAL PERMANENT COLORING OF HAIR | UNILEVER PLC (GB) | 2002-09-26 | — | — | WO | claimed |
| WO-2002003938-A1 | IODO-CONTAINING ORGANIC COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | CLAIROL INCORPORATED (US) | 2002-01-17 | — | — | WO | claimed |
| EP-1129688-A1 | Hair coloring composition using an inorganic peroxymonosulfate salt as an oxidation agent. | Bristol-Myers Squibb Company (US) | 2001-09-05 | — | — | EP | claimed |
| WO-2001056538-A1 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P&G-CLAIROL, INC. (US) | 2001-08-09 | — | — | WO | claimed |
| US-6200353-B1 | Coupler for use in oxidative hair dyeing | BRISTOL MYERS SQUIBB COMPANY | 2001-03-13 | — | — | US | claimed |