Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069473 | 0.84 | CYP1A2 (0.39) | CYP1A2GABRR1LTA4HGABRPGABRD | |
| SCHEMBL13176582 | 0.81 | CYP1A2 (0.65) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL10529024 | 0.81 | CYP1A2 (0.65) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL12324532 | 0.81 | CYP1A2 (0.65) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL10045844 | 0.79 | CYP1A2 (0.62) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL24823343 | 0.77 | CYP1A2 (0.60) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL23876512 | 0.77 | CYP1A2 (0.60) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL24233197 | 0.77 | CYP1A2 (0.60) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL5139179 | 0.77 | GABRR1 (0.72) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL16425734 | 0.76 | CYP1A2 (0.65) | CYP1A2GABRR1LTA4HBLMACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883645-B1 | DERIVATIVES OF 4-OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC (CA) | 2011-06-29 | — | — | EP | disclosed |