Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12601003 | 0.84 | CYP1A2 (0.60) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL15774679 | 0.80 | ALOX15 (0.46) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL14895150 | 0.80 | ALOX15 (0.46) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL487784 | 0.80 | ALOX15 (0.46) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL26475764 | 0.78 | CYP1A2 (0.65) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21026616 | 0.78 | ALDH1A1 (0.43) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL15601864 | 0.78 | CYP1A2 (0.65) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL6665196 | 0.78 | CYP1A2 (0.65) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10586505 | 0.76 | CYP1A2 (0.39) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28312273 | 0.76 | CYP1A2 (0.39) | CYP1A2GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979334-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Dong Wha Pharmaceutical. Ind. Co., Ltd. (KR) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007089101-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG WHA PHARMACEUTICAL IND.CO., LTD. (KR) | 2007-08-09 | — | — | WO | disclosed |