Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | GUSB | P08236 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 4/20 | 0.35 |
| ▸ | PYGM | P11217 | 4/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12601700 | 0.87 | CNR2 (0.57) | CNR2HRH4PYGLPYGMMLLT1 | |
| SCHEMBL12601714 | 0.87 | CNR2 (0.57) | CNR2HRH4PYGLPYGMMLLT1 | |
| SCHEMBL12601719 | 0.86 | CNR2 (0.71) | CNR2HRH4PYGLPYGMSMYD3 | |
| SCHEMBL12601721 | 0.86 | CNR2 (0.56) | CNR2HRH4PYGLPYGMMLLT1 | |
| SCHEMBL12601713 | 0.86 | CNR2 (0.56) | CNR2HRH4PYGLPYGMMLLT1 | |
| SCHEMBL12601717 | 0.85 | CNR2 (0.54) | CNR2DRD2PYGLPYGMKDM4E | |
| SCHEMBL1572507 | 0.84 | CNR2 (0.76) | CNR2HRH4GUSBHTR1ADRD2 | |
| SCHEMBL1572505 | 0.84 | CNR2 (0.76) | CNR2HRH4GUSBHTR1ADRD2 | |
| SCHEMBL12601718 | 0.81 | CNR2 (0.51) | CNR2PYGLPYGMMLLT1KDM4E | |
| SCHEMBL1155914 | 0.72 | MLLT1 (0.58) | HRH4GUSBHTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943658-B2 | Indole indane amide compounds useful as CB2 agonists and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-17 | — | — | US | disclosed |
| US-20090041722-A1 | INDOLE INDANE AMIDE COMPOUNDS USEFUL AS CB2 AGONISTS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090041722-A1 | INDOLE INDANE AMIDE COMPOUNDS USEFUL AS CB2 AGONISTS AND METHOD | CNR2, CNR1, GPR68 | CNR2 1/4885HRH4 21/4885GUSB 4619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.