Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15020560 | 0.90 | TSHR (0.50) | SMN1; SMN2HTTLMNAACHETSHR | |
| SCHEMBL31453899 | 0.90 | TSHR (0.50) | SMN1; SMN2HTTLMNAACHETSHR | |
| SCHEMBL14047520 | 0.81 | HPGD (0.44) | SMN1; SMN2LMNAACHETSHRCYP3A4 | |
| SCHEMBL11555661 | 0.78 | HTT (0.44) | SMN1; SMN2HTTLMNAACHETSHR | |
| SCHEMBL8620844 | 0.78 | INPPL1 (0.52) | SMN1; SMN2HTTLMNATSHRCYP2C9 | |
| SCHEMBL5851888 | 0.78 | HTT (0.47) | SMN1; SMN2HTTLMNATSHRTDP1 | |
| SCHEMBL27430826 | 0.76 | KDM4E (0.46) | SMN1; SMN2HTTLMNAACHETSHR | |
| SCHEMBL13301694 | 0.76 | LMNA (0.41) | SMN1; SMN2HTTLMNAACHETSHR | |
| SCHEMBL25352073 | 0.75 | CYP3A4 (0.47) | SMN1; SMN2TSHRCYP3A4TDP1CYP2C9 | |
| SCHEMBL108984 | 0.74 | CYP3A4 (0.50) | SMN1; SMN2LMNAACHETSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110109857-A1 | LIQUID CRYSTAL DISPLAY DEVICE | JAPAN DISPLAY EAST INC. (JP) | 2011-05-12 | — | — | US | disclosed |