Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 7/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12606068 | 0.90 | CMA1 (0.41) | CMA1F2PRSS1ITGB3ITGA2B | |
| SCHEMBL12606119 | 0.89 | CMA1 (0.45) | CMA1F2PRSS1CTSK | |
| SCHEMBL12606207 | 0.89 | F2 (0.39) | CMA1F2PRSS1ITGB3ITGA2B | |
| SCHEMBL14628551 | 0.89 | F2 (0.39) | CMA1F2PRSS1ITGB3ITGA2B | |
| SCHEMBL12605461 | 0.89 | F2 (0.44) | CMA1F2PRSS1ITGB3ITGA2B | |
| SCHEMBL16329136 | 0.89 | F2 (0.44) | CMA1F2PRSS1ITGB3ITGA2B | |
| SCHEMBL12606121 | 0.89 | CMA1 (0.39) | CMA1F2PRSS1ITGB3ITGA2B | |
| SCHEMBL12606122 | 0.89 | CMA1 (0.39) | CMA1F2PRSS1ITGB3ITGA2B | |
| SCHEMBL12605920 | 0.88 | F2 (0.39) | CMA1F2PRSS1CTSKELANE | |
| SCHEMBL10139036 | 0.86 | CMA1 (0.41) | CMA1F2PRSS1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110117057-A1 | NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2011-05-19 | — | — | US | disclosed |
| US-20110117057-A1 | NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117057-A1 | NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | HPN, TMPRSS15, VIP | CMA1 114/4885F2 569/4885PRSS1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.