Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1994629 | 0.90 | PTGDR2 (0.46) | LMNAPPARDFFAR1PLA2G1BPTPN1 | |
| SCHEMBL12606354 | 0.88 | PTGER1 (0.41) | PTPN1F2ELANEPTGDR2 | |
| SCHEMBL12608039 | 0.83 | PTPN1 (0.46) | LMNAPPARDFFAR1PTPN1PPARA | |
| SCHEMBL12605590 | 0.81 | PTGDR2 (0.40) | PPARDTDP1PTGDR2 | |
| SCHEMBL1997301 | 0.79 | PTGDR2 (0.46) | PPARDPTPN1MAPTHTTTDP1 | |
| SCHEMBL12607455 | 0.78 | PTGDR2 (0.50) | PPARDFFAR1PTPN1PPARAPPARG | |
| SCHEMBL1993719 | 0.77 | PTGDR2 (0.56) | F2ELANETDP1L3MBTL1PTGDR2 | |
| SCHEMBL12606349 | 0.74 | PTGDR2 (0.48) | PPARDFFAR1PTPN1PPARAPPARG | |
| SCHEMBL27912754 | 0.73 | ALDH1A1 (0.46) | MAPTCYP1A2 | |
| SCHEMBL1992093 | 0.72 | PTGDR2 (0.53) | LMNAPPARDFFAR1PTPN1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336113-A1 | CRTH2 Receptor Ligands for Medical Use | 7TM Pharma A/S (DK) | 2011-06-22 | — | — | EP | disclosed |