SCHEMBL12606393

COC1C(OC)[C@H](O[C@H]2O[C@@H](COS(=O)(=O)O)[C@@H](O[C@@H]3OC(C(=O)O)[C@@H](O[C@H]4OC(COS(=O)(=O)O)[C@@H](OC)[C@H](OC)C4N)[C@H](OC)C3OC)C(OSOOO)C2OSOOO)[C@H](C(=O)O)O[C@H]1O[C@@H]1C(COS(=O)(=O)O)O[C@H](OC)C(OSOOO)[C@H]1OSOOO

nearest known ligand 0.60

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	SERPINC1	P01008	3/20	0.60

▸	F10	P00742	6/20	0.43

▸	FGF1	P05230	4/20	0.42

▸	F2	P00734	1/20	0.41

▸	HPSE	Q9Y251	5/20	0.35

▸	FGF2	P09038	1/20	0.35

▸	BDNF	P23560	2/20	0.31

▸	PTN	P21246	1/20	0.31

▸	MDK	P21741	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12606391	0.91	SERPINC1 (0.58)	SERPINC1F10FGF1F2HPSE
SCHEMBL13039102	0.90	SERPINC1 (0.57)	SERPINC1F10FGF1F2HPSE
SCHEMBL14363911	0.90	SERPINC1 (0.57)	SERPINC1F10FGF1F2HPSE
SCHEMBL12606386	0.87	SERPINC1 (0.54)	SERPINC1F10FGF1F2HPSE
SCHEMBL12606421	0.86	SERPINC1 (0.53)	SERPINC1F10FGF1F2HPSE
SCHEMBL12606383	0.84	SERPINC1 (0.51)	SERPINC1F10FGF1F2HPSE
SCHEMBL13039108	0.82	SERPINC1 (0.54)	SERPINC1F10FGF1F2HPSE
Idraparinux SCHEMBL29382311	0.81	SERPINC1 (0.85)	SERPINC1F10FGF1F2HPSE
SCHEMBL29407493	0.81	SERPINC1 (0.85)	SERPINC1F10FGF1F2HPSE
Idraparinux SCHEMBL427808	0.81	SERPINC1 (0.85)	SERPINC1F10FGF1F2HPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7943595-B2	Polysaccharides with antithrombotic activity comprising at least one covalent bond with biotin or a biotin derivative	SANOFI-AVENTIS (FR)	2011-05-17	—	—	US	disclosed