SCHEMBL12609403

SCHEMBL12609403

C[C@H](NC(=O)[C@H](Cc1ccc(Br)cc1)CP(=O)(O)[C@H](C)N)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MME P08473 6/20 0.78
ANPEP P15144 2/20 0.78
ECE1 P42892 1/20 0.54
ENPEP Q07075 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1764342 1.00 MME (0.78) MMEANPEPECE1ENPEP
SCHEMBL20526394 0.92 MME (0.67) MMEANPEPECE1
SCHEMBL29684736 0.87 MME (1.00) MMEANPEP
SCHEMBL20526397 0.87 MME (1.00) MMEANPEP
SCHEMBL1764418 0.87 MME (1.00) MMEANPEP
SCHEMBL4992398 0.87 MME (1.00) MMEANPEP
SCHEMBL4992386 0.87 MME (1.00) MMEANPEP
SCHEMBL12609398 0.87 MME (1.00) MMEANPEP
SCHEMBL20526396 0.87 MME (0.60) MMEANPEPECE1ENPEP
SCHEMBL1764058 0.86 ANPEP (0.57) MMEANPEPENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110117069-A1 METHOD FOR ACTIVATING REGULATORY T-CELLS IMTM GMBH (DE) 2011-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117069-A1 METHOD FOR ACTIVATING REGULATORY T-CELLS ANPEP, DNPEP, RNPEP MME 72/4885ANPEP 1/4885ECE1 446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.