Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.60 |
| ▸ | ANPEP | P15144 | 2/20 | 0.60 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20526394 | 0.96 | MME (0.67) | MMEANPEPECE1 | |
| SCHEMBL20526392 | 0.88 | MME (0.64) | MMEANPEPECE1ENPEP | |
| SCHEMBL20575159 | 0.88 | MME (0.79) | MMEANPEP | |
| SCHEMBL28499352 | 0.88 | MME (0.45) | MMEANPEPECE1 | |
| SCHEMBL12596644 | 0.88 | MME (0.79) | MMEANPEP | |
| SCHEMBL12609403 | 0.87 | MME (0.78) | MMEANPEPECE1ENPEP | |
| SCHEMBL1764342 | 0.87 | MME (0.78) | MMEANPEPECE1ENPEP | |
| SCHEMBL28499354 | 0.84 | MME (0.42) | MMEANPEPECE1 | |
| SCHEMBL20526395 | 0.83 | ENPEP (0.52) | MMEANPEPECE1ENPEP | |
| SCHEMBL20575439 | 0.80 | MME (0.73) | MMEANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3592361-B1 | AMINOPHOSPHINIC DERIVATIVES FOR PREVENTING AND TREATING OCULAR INFLAMMATION | IACTA PHARMACEUTICALS INC (PR) | 2023-09-13 | — | — | EP | claimed |
| US-10688113-B2 | Methods of treating eye pain with aminophosphinic derivatives | PHARMALEADS (FR) | 2020-06-23 | — | — | US | claimed |
| US-20190167701-A1 | Methods of Treating Eye Pain With Aminophosphinic Derivatives | PHARMALEADS (FR) | 2019-06-06 | — | — | US | claimed |
| US-20180344753-A1 | AMINOPHOSPHINIC DERIVATIVES FOR PREVENTING AND TREATING EYE PAIN | PHARMALEADS (FR) | 2018-12-06 | — | — | US | claimed |
| EP-3383403-A1 | AMINOPHOSPHINIC DERIVATIVES FOR PREVENTING AND TREATING EYE PAIN | Pharmaleads (FR) | 2018-10-10 | — | — | EP | claimed |
| US-10688113-B2 | Methods of treating eye pain with aminophosphinic derivatives | PHARMALEADS (FR) | 2020-06-23 | — | — | US | disclosed |
| US-20190167701-A1 | Methods of Treating Eye Pain With Aminophosphinic Derivatives | PHARMALEADS (FR) | 2019-06-06 | — | — | US | disclosed |
| US-20180344753-A1 | AMINOPHOSPHINIC DERIVATIVES FOR PREVENTING AND TREATING EYE PAIN | PHARMALEADS (FR) | 2018-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190167701-A1 | Methods of Treating Eye Pain With Aminophosphinic Derivatives | P2RX7, HRH3, P2RX6 | MME 3364/4885ANPEP 1779/4885ECE1 2402/4885 |
| US-10688113-B2 | Methods of treating eye pain with aminophosphinic derivatives | P2RX7, HRH3, P2RX6 | MME 3364/4885ANPEP 1779/4885ECE1 2402/4885 |
| US-20180344753-A1 | AMINOPHOSPHINIC DERIVATIVES FOR PREVENTING AND TREATING EYE PAIN | P2RX7, P2RY6, HRH3 | MME 3636/4885ANPEP 973/4885ECE1 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.