Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 19/20 | 0.45 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12610748 | 1.00 | HSD11B1 (0.45) | HSD11B1HSD11B2DRD4 | |
| SCHEMBL12610970 | 0.96 | HSD11B1 (0.43) | HSD11B1HSD11B2 | |
| SCHEMBL12610860 | 0.93 | HSD11B1 (0.45) | HSD11B1HSD11B2 | |
| SCHEMBL12610727 | 0.91 | HSD11B1 (0.44) | HSD11B1HSD11B2 | |
| SCHEMBL12610712 | 0.91 | HSD11B1 (0.45) | HSD11B1HSD11B2 | |
| SCHEMBL12611085 | 0.90 | HSD11B1 (0.44) | HSD11B1 | |
| SCHEMBL12610718 | 0.90 | HSD11B1 (0.51) | HSD11B1 | |
| SCHEMBL12610836 | 0.90 | HSD11B1 (0.47) | HSD11B1HSD11B2 | |
| SCHEMBL12610678 | 0.90 | HSD11B1 (0.44) | HSD11B1HSD11B2 | |
| SCHEMBL12610805 | 0.90 | HSD11B1 (0.44) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012128582-A2 | A COMPOUND FOR INHIBITING HUMAN 11-β-HYDROXY STEROID DEHYDROGENASE TYPE 1, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2012-09-27 | — | — | WO | disclosed |