SCHEMBL126126

SCHEMBL126126

O=c1[nH]ncc2c1cc(Br)n2COCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
HSD17B10 Q99714 3/20 0.43
KDM4E B2RXH2 3/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CYP1A2 P05177 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TRPC5 Q9UL62 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
USP2 O75604 2/20 0.38
PARP1 P09874 3/20 0.35
PRKCI P41743 1/20 0.35
PDE4B Q07343 1/20 0.35
TSHR P16473 4/20 0.35
POLB P06746 1/20 0.34
MAPK1 P28482 1/20 0.33
KDM4A O75164 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL128976 0.77 HSD17B10 (0.42) ALDH1A1HSD17B10KDM4ECYP2C9CYP2C19
SCHEMBL128825 0.71 NPC1 (0.41) ALDH1A1KDM4EKMT2ATSHRLMNA
SCHEMBL132702 0.71 ALDH1A1 (0.42) ALDH1A1KDM4ECYP2C9CYP2C19USP2
SCHEMBL128251 0.70 PDE4D (0.37) CYP2C9CYP2C19PDE4B
SCHEMBL130534 0.69 ALDH1A1 (0.39) ALDH1A1HSD17B10KDM4ECYP2C9CYP2C19
SCHEMBL1781279 0.67 ALDH1A1 (0.53) ALDH1A1CYP2C9CYP2C19L3MBTL1MEN1
SCHEMBL127842 0.67 ALDH1A1 (0.40) ALDH1A1HSD17B10KDM4ECYP2C9CYP2C19
SCHEMBL30728403 0.67 CYP19A1 (0.57) ALDH1A1KDM4ECYP2C19CYP1A2L3MBTL1
SCHEMBL128833 0.66 ALDH1A1 (0.39) ALDH1A1HSD17B10KDM4ECYP2C9CYP2C19
SCHEMBL132426 0.66 ALDH1A1 (0.39) ALDH1A1HSD17B10KDM4ECYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115632670-A CMOS current multiplexing type self-oscillation receiver front end 成都信息工程大学 2023-01-20 CN claimed
CN-111974616-B Dispensing method, dispensing device, computer equipment and storage medium 广东安达智能装备股份有限公司 2023-01-03 CN claimed
CN-115358026-A Five-hole probe data processing method based on multivariate linear regression and surface fitting 大连温特纳科技有限公司 2022-11-18 CN claimed
CN-111527086-A Diazacyclooctane compounds for their cosmetic use 莱雅公司 2020-08-11 CN claimed
EP-0793679-A1 ETHYLENE HOMOPOLYMERIZATION USING GROUP 3 METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-09-10 EP claimed
WO-1996016095-A1 ETHYLENE HOMOPOLYMERIZATION USING GROUP 3 METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1996-05-30 WO claimed
CN-118342505-A Robot polishing track planning method and device based on machine vision 北京理工大学 2024-07-16 CN disclosed
US-20230414520-A1 IMMEDIATE RELEASE DOSAGE FORM KENVUE BRANDS LLC 2023-12-28 US disclosed
US-11779541-B2 Immediate release dosage form JOHNSON & JOHNSON CONSUMER INC. (US) 2023-10-10 US disclosed
CN-116776484-A Design method for shape modification tooth profile of worm grinding roller 黄河科技学院 2023-09-19 CN disclosed
CN-116761991-A Force input positioning 剑桥触控科技有限公司 2023-09-15 CN disclosed
WO-2023041727-A1 BATTERY MEASURING SYSTEM Heimdalytics GmbH (DE) 2023-03-23 WO disclosed
CN-115701575-A Touch sensing unit and display device 三星显示有限公司 2023-02-10 CN disclosed
EP-0339043-A1 FORMATION OF ELECTRIC FIELD DISCHARGES COMBUSTION ELECTROMAGNETICS INC. (US) 1989-11-02 EP disclosed
US-4866349-A Power efficient sustain drivers and address drivers for plasma panel THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1989-09-12 US disclosed
US-4841925-A Enhanced flame ignition for hydrocarbon fuels COMBUSTION ELECTROMAGNETICS, INC. (US) 1989-06-27 US disclosed
WO-1988004729-A1 FORMATION OF ELECTRIC FIELD DISCHARGES COMBUSTION ELECTROMAGNETICS, INC. (US) 1988-06-30 WO disclosed
EP-0261584-A2 Method for controlling cells and pixels of plasma panels, plasma display panels, electroluminescent panels, lcd's or that like and a circuit for carrying out the method The Board of Trustees of the University of Illinois (US) 1988-03-30 EP disclosed
EP-0143533-A2 Image data expanding and/or contracting method and apparatus MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1985-06-05 EP disclosed
EP-0014630-A1 Thermodynamic engine and its use as a motor or as a refrigerating machine Clavier, Philippe (FR) 1980-08-20 EP disclosed