SCHEMBL12615495

SCHEMBL12615495

CC(C)[C@H](CO)NCc1nc(-c2ccccc2F)ccc1F.O=Cc1nc(-c2ccccc2F)ccc1F

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TRPV3 Q8NET8 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12538187 0.90 TRPV3 (1.00) TRPV3
SCHEMBL12615570 0.84 TRPV3 (0.83) TRPV3
SCHEMBL12615576 0.84 TRPV3 (0.82) TRPV3
SCHEMBL12615486 0.83 TRPV3 (0.83) TRPV3
SCHEMBL12616658 0.81 TRPV3 (0.55) TRPV3
SCHEMBL12538243 0.81 TRPV3 (0.78) TRPV3
SCHEMBL12616205 0.81 TRPV3 (0.83) TRPV3
SCHEMBL12537981 0.81 TRPV3 (0.82) TRPV3
SCHEMBL12538698 0.81 TRPV3 (0.84) TRPV3
SCHEMBL12537957 0.80 TRPV3 (0.80) TRPV3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012129491-A1 TRPV3 MODULATORS ABBOTT LABORATORIES (US) 2012-09-27 — — WO disclosed
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