Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5076270 | 0.98 | LMNA (0.53) | LMNAEP300MAPTFAAHTERT | |
| SCHEMBL128928 | 0.94 | LMNA (0.47) | LMNAHCAR2MAPTFAAHALDH1A1 | |
| SCHEMBL127506 | 0.85 | HCAR2 (0.45) | LMNAHCAR2ALDH1A1 | |
| SCHEMBL8893919 | 0.81 | CNR2 (0.39) | LMNAMAPTALDH1A1HPGDCNR2 | |
| SCHEMBL8896256 | 0.80 | LMNA (0.40) | LMNACNR2 | |
| SCHEMBL8896613 | 0.80 | LMNA (0.40) | LMNACNR2 | |
| SCHEMBL8895455 | 0.80 | LMNA (0.40) | LMNACNR2 | |
| SCHEMBL8895615 | 0.80 | LMNA (0.40) | LMNACNR2 | |
| SCHEMBL8894011 | 0.80 | TSHR (0.40) | LMNACNR2 | |
| SCHEMBL8896255 | 0.80 | LMNA (0.40) | LMNACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
| US-7358286-B2 | Stabilizer system for stabilizing PVC | CHEMTURA VINYL ADDITIVES GMBH (DE) | 2008-04-15 | — | — | US | disclosed |
| EP-1583796-B1 | STABILIZER SYSTEM FOR STABILIZING PVC | CHEMTURA VINYL ADDITIVES GMBH (DE) | 2007-10-24 | — | — | EP | disclosed |
| US-20060052497-A1 | Stabilizer system for stabilizing pvc | CROMPTON VINYL ADDITIVES GMBH (DE) | 2006-03-09 | — | — | US | disclosed |
| EP-1583796-A2 | STABILIZER SYSTEM FOR STABILIZING PVC | Crompton Vinyl Additives GmbH (DE) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004065470-A2 | STABILIZER SYSTEM FOR STABILIZING PVC | CROMPTON VINYL ADDITIVES GMBH (DE) | 2004-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036453-A1 | Pyrrolopyridazinone Compound | CBR3, CBR1, CYC1 | LMNA 1679/4885HCAR2 99/4885EP300 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.