Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 16/20 | 0.74 |
| ▸ | GSK3B | P49841 | 15/20 | 0.74 |
| ▸ | PRKCG | P05129 | 13/20 | 0.74 |
| ▸ | PRKCA | P17252 | 12/20 | 0.74 |
| ▸ | PRKCE | Q02156 | 7/20 | 0.74 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.74 |
| ▸ | CDK1 | P06493 | 2/20 | 0.72 |
| ▸ | CDK2 | P24941 | 1/20 | 0.72 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.72 |
| ▸ | PRKCH | P24723 | 3/20 | 0.64 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.64 |
| ▸ | SRC | P12931 | 2/20 | 0.64 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.62 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.62 |
| ▸ | PRKACA | P17612 | 1/20 | 0.62 |
| ▸ | PRKACG | P22612 | 1/20 | 0.62 |
| ▸ | PRKACB | P22694 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336971 | 1.00 | PRKCB (0.74) | PRKCBGSK3BPRKCGPRKCAPRKCE | |
| SCHEMBL29800011 | 1.00 | PRKCB (0.74) | PRKCBGSK3BPRKCGPRKCAPRKCE | |
| SCHEMBL22765422 | 1.00 | PRKCB (0.74) | PRKCBGSK3BPRKCGPRKCAPRKCE | |
| SCHEMBL30336889 | 1.00 | PRKCB (0.74) | PRKCBGSK3BPRKCGPRKCAPRKCE | |
| SCHEMBL22765333 | 0.89 | PRKCB (0.67) | PRKCBGSK3BPRKCGPRKCAPRKCE | |
| SCHEMBL12629226 | 0.88 | PRKCB (0.65) | PRKCBGSK3BPRKCGPRKCAPRKCE | |
| SCHEMBL25778145 | 0.88 | GSK3B (0.90) | PRKCBGSK3BPRKCGPRKCAPRKCE | |
| SCHEMBL4346607 | 0.85 | GSK3B (1.00) | PRKCBGSK3BPRKCGPRKCAPRKCE | |
| SCHEMBL22765525 | 0.85 | GSK3B (0.97) | PRKCBGSK3BPRKCGPRKCAPRKCE | |
| SCHEMBL4343058 | 0.85 | GSK3B (1.00) | PRKCBGSK3BPRKCGPRKCAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815590-B2 | Composition and method for differentiation of human embryonic stem cells | STEM CELLS FOR SAFER MEDICINES LIMITED (GB) | 2014-08-26 | — | — | US | disclosed |
| US-8815590-B2 | Composition and method for differentiation of human embryonic stem cells | STEM CELLS FOR SAFER MEDICINES LIMITED (GB) | 2014-08-26 | — | — | US | disclosed |
| US-20130028872-A1 | COMPOSITION AND METHOD FOR DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS | STEM CELLS FOR SAFER MEDICINES LIMITED (GB) | 2013-01-31 | — | — | US | disclosed |
| US-20130028872-A1 | COMPOSITION AND METHOD FOR DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS | STEM CELLS FOR SAFER MEDICINES LIMITED (GB) | 2013-01-31 | — | — | US | disclosed |
| WO-2011064549-A2 | COMPOSITION AND METHOD FOR DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS | STEM CELLS FOR SAFER MEDICINES LIMITED (GB) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130028872-A1 | COMPOSITION AND METHOD FOR DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS | ALPG, GSK3B, GSK3A | PRKCB 158/4885GSK3B 2/4885PRKCG 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.