SCHEMBL12630195

SCHEMBL12630195

C[C@@H](NS(=O)(=O)c1ccc(CBr)cc1)c1ccc(F)c(OCC2CC2)c1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ DUT P33316 18/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1409522 0.89 DUT (0.69) DUT
SCHEMBL1409521 0.89 DUT (0.69) DUT
SCHEMBL12629717 0.82 DUT (0.67) DUT
SCHEMBL20351684 0.82 DUT (0.59) DUT
SCHEMBL12630227 0.82 DUT (0.67) DUT
SCHEMBL21534021 0.81 DUT (0.63) DUT
SCHEMBL21350467 0.81 DUT (0.58) DUT
SCHEMBL21778437 0.81 DUT (0.63) DUT
SCHEMBL20187881 0.79 DUT (0.56) DUT
SCHEMBL20187878 0.79 DUT (0.56) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011065545-A1 5-FLUOROURACIL COMPOUND HAVING dUTPase-INHIBITING ACTIVITY OR SALT THEREOF 大鵬薬品工業株式会社 (JP) 2011-06-03 — — WO disclosed
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