SCHEMBL12630872

SCHEMBL12630872

C#C[C@@H](C)Oc1cccc([C@@H](C)NS(=O)(=O)CCCOCn2cc(F)c(=O)[nH]c2=O)c1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ DUT P33316 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12630870 1.00 DUT (0.77) DUT
SCHEMBL12629547 0.89 DUT (0.76) DUT
SCHEMBL12630241 0.89 DUT (0.77) DUT
SCHEMBL12630874 0.87 DUT (0.77) DUT
SCHEMBL12629551 0.87 DUT (0.77) DUT
SCHEMBL1409565 0.87 DUT (1.00) DUT
SCHEMBL1408920 0.87 DUT (1.00) DUT
SCHEMBL1408918 0.87 DUT (1.00) DUT
SCHEMBL12630541 0.85 DUT (0.77) DUT
SCHEMBL12630246 0.85 DUT (0.64) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011065545-A1 5-FLUOROURACIL COMPOUND HAVING dUTPase-INHIBITING ACTIVITY OR SALT THEREOF 大鵬薬品工業株式会社 (JP) 2011-06-03 — — WO disclosed
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