SCHEMBL1263211

SCHEMBL1263211

CCCCCc1ccc2c(c1)C(C)=CC(C)(C)N2

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.71
▸ KDM4E B2RXH2 6/20 0.71
▸ HPGD P15428 6/20 0.71
▸ GAA P10253 1/20 0.71
▸ MAPT P10636 3/20 0.68
▸ TDP1 Q9NUW8 3/20 0.68
▸ MEN1 O00255 3/20 0.68
▸ KMT2A Q03164 3/20 0.68
▸ L3MBTL1 Q9Y468 2/20 0.68
▸ MAPK1 P28482 1/20 0.68
▸ HSD17B10 Q99714 5/20 0.56
▸ CYP3A4 P08684 3/20 0.55
▸ CYP1A2 P05177 2/20 0.55
▸ CYP2D6 P10635 2/20 0.55
▸ CYP2C9 P11712 2/20 0.55
▸ CYP2C19 P33261 2/20 0.55
▸ LMNA P02545 2/20 0.55
▸ ALOX15 P16050 1/20 0.55
▸ ALOX12 P18054 1/20 0.55
▸ HIF1A Q16665 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7069498 0.99 ALDH1A1 (0.69) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL7073745 0.99 ALDH1A1 (0.69) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL7071614 0.99 ALDH1A1 (0.69) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL97245 0.99 ALDH1A1 (0.69) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL7044150 0.99 ALDH1A1 (0.69) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL7071108 0.96 ALDH1A1 (0.73) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL95135 0.92 ALDH1A1 (0.61) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL7073326 0.90 ALDH1A1 (0.77) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL28118940 0.82 ALDH1A1 (0.49) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL11399430 0.79 MAPT (0.55) ALDH1A1KDM4EHPGDGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020081726-A1 METHODS OF TREATING MENOPAUSAL SYMPTOMS USING LOW DOSE PROGESTERONE STADLER SARAH SHEEHAN (US) 2020-04-23 — — WO claimed
EP-1620060-B1 METHODS AND DEVICES FOR THE SUSTAINED RELEASE OF MULTIPLE DRUGS GEN HOSPITAL CORP (US) 2010-03-24 — — EP claimed
EP-1620060-A4 METHODS AND DEVICES FOR THE SUSTAINED RELEASE OF MULTIPLE DRUGS GEN HOSPITAL CORP (US) 2007-11-28 — — EP claimed
US-20070196433-A1 Methods and devices for the sustained release of multiple drugs THE MASSACHUSETTS GENERAL HOSPITAL CORPORATION 2007-08-23 — — US claimed
EP-1620060-A2 METHODS AND DEVICES FOR THE SUSTAINED RELEASE OF MULTIPLE DRUGS THE GENERAL HOSPITAL CORPORATION (US) 2006-02-01 — — EP claimed
WO-2004096151-A2 METHODS AND DEVICES FOR THE SUSTAINED RELEASE OF MULTIPLE DRUGS THE GENERAL HOSPITAL CORPORATION (US) 2004-11-11 — — WO claimed
EP-2779996-B1 DRUG DELIVERY SYSTEM FOR SUSTAINED DELIVERY OF BIOACTIVE AGENTS UPM KYMMENE CORP (FI) 2024-04-10 — — EP disclosed
US-11389537-B2 Drug delivery system for sustained delivery of bioactive agents UPM-KYMMENE CORPORATION (FI) 2022-07-19 — — US disclosed
US-20210386757-A1 Methods of Treating Menopausal Symptoms Using Low Dose Progesterone STADLER SARAH S (US) 2021-12-16 — — US disclosed
EP-3395332-A1 HORMONE SOFTGEL CAPSULES AND A PROCESS FOR THE PREPARATION THEREOF Chemo Research, S.L. (ES) 2018-10-31 — — EP disclosed
EP-2456421-B1 MULTI-LAYERED GRADIENT VAGINAL RING THE POPULATION COUNCIL INC (US) 2017-04-05 — — EP disclosed
US-20140322327-A1 DRUG DELIVERY SYSTEM FOR SUSTAINED DELIVERY OF BIOACTIVE AGENTS UPM-KYMMENE CORPORATION (FI) 2014-10-30 — — US disclosed
EP-2779996-A1 DRUG DELIVERY SYSTEM FOR SUSTAINED DELIVERY OF BIOACTIVE AGENTS UPM-Kymmene Corporation (FI) 2014-09-24 — — EP disclosed
US-5696133-A ADMINISTERING COMPOUND WHICH MODULATES ACTIVITY OF PROGESTERONE RECEPTOR LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-12-09 — — US disclosed
US-5693647-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-12-02 — — US disclosed
US-5693646-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-12-02 — — US disclosed
US-5688808-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-11-18 — — US disclosed
US-5688810-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-11-18 — — US disclosed
EP-0800519-A1 STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS, INC. (US) 1997-10-15 — — EP disclosed
WO-1996019458-A2 STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS INCORPORATED (US) 1996-06-27 — — WO disclosed
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