SCHEMBL1263258

SCHEMBL1263258

Cc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.68
USP2 O75604 1/20 0.68
GAA P10253 1/20 0.68
KMT2A Q03164 1/20 0.68
KEAP1 Q14145 1/20 0.68
NFE2L2 Q16236 1/20 0.68
HPGD P15428 4/20 0.63
LMNA P02545 3/20 0.63
HTT P42858 2/20 0.63
ALDH1A1 P00352 1/20 0.63
CYP1A2 P05177 1/20 0.63
PGR P06401 1/20 0.63
CYP2D6 P10635 1/20 0.63
SLC6A2 P23975 1/20 0.63
PDE4A P27815 1/20 0.63
MAPK1 P28482 1/20 0.63
CYP2C19 P33261 1/20 0.63
HRH1 P35367 1/20 0.63
SLC6A3 Q01959 1/20 0.63
PDE4D Q08499 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29701295 1.00 MEN1 (0.68) MEN1USP2GAAKMT2AKEAP1
Sulfuric Acid SCHEMBL9392499 0.93 KMT2A (0.60) MEN1USP2GAAKMT2AKEAP1
SCHEMBL11350747 0.89 NPC1 (0.64) MEN1USP2GAAKMT2AKEAP1
SCHEMBL15779739 0.88 GAA (0.53) MEN1USP2GAAKMT2AKEAP1
SCHEMBL9076089 0.86 POLB (0.55) MEN1USP2GAAKMT2AKEAP1
SCHEMBL147250 0.85 CSNK2A1 (0.63) MEN1USP2GAAKMT2AKEAP1
SCHEMBL15044104 0.85 NPC1 (0.58) MEN1USP2GAAKMT2AKEAP1
SCHEMBL29823118 0.85 CSNK2A1 (0.63) MEN1USP2GAAKMT2AKEAP1
SCHEMBL28384878 0.85 AKR1C3 (0.61) MEN1USP2GAAKMT2AKEAP1
SCHEMBL1758035 0.84 NPC1 (0.56) MEN1KMT2AHPGDLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 403 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081057-A Sole with flexibility and rebound resilience, polyurethane composition and preparation method thereof 温州市添荣鞋材有限公司 2024-12-06 CN claimed
CN-113861927-B Moisture-cured polyurethane hot melt adhesive with high initial adhesion strength and high adhesion fastness and preparation method thereof 辽宁恒星精细化工有限公司 2023-09-26 CN claimed
WO-2023162998-A1 COMPOSITION INCLUDING IODO COMPOUND AND USE FOR SAME 東ソー株式会社 2023-08-31 WO claimed
CN-113321926-B Efficient blending modified polyether type TPU and application thereof 东莞市鼎誉新材料有限公司 2022-12-16 CN claimed
CN-112708101-B Preparation method of thermoplastic polyurethane elastomer for reactive hot melt adhesive 辽宁恒星精细化工有限公司 2022-07-12 CN claimed
CN-113861927-A Moisture-curing polyurethane hot melt adhesive with high initial adhesion strength and high bonding fastness and preparation method thereof 辽宁恒星精细化工有限公司 2021-12-31 CN claimed
CN-113321926-A High-efficiency blended modified polyether TPU and application thereof 东莞市鼎誉新材料有限公司 2021-08-31 CN claimed
CN-112708101-A Preparation method of thermoplastic polyurethane elastomer for reactive hot melt adhesive 辽宁恒星精细化工有限公司 2021-04-27 CN claimed
CN-108341985-B Micro-foaming flame-retardant polyurethane material and preparation method thereof 广东柏胜新材料股份有限公司 2020-12-22 CN claimed
CN-111040717-A Moisture curing reaction type polyurethane hot melt adhesive and preparation method thereof 惠州市远安新材料有限公司 2020-04-21 CN claimed
CN-101993652-A Environment-friendly polyurethane coating layer for synthetic court and preparation method thereof SHANDONG DONGDA INOV POLYURETHANE CO LTD 2011-03-30 CN claimed
CN-101130680-B Environment protection type single-component polyurethane binder, production and use method of the same SHANGDONG DONG DA INOV POLYUERTHANE CO LTD 2011-03-23 CN claimed
CN-101096560-B Environment-friendly type polyurethane combined material and using method SHANGDONG DONG DA INOV POLYUERTHANE CO LTD 2010-12-15 CN claimed
CN-1865324-B Low temperature resistant polyvinyl chloride salt film for anti-aging Dongying tianyuan plastic industry co ltd 2010-12-08 CN claimed
CN-101402719-A Transparent high-elasticity thermoplastic polyurethane and method of producing the same GUANGZHOU LUSHAN CHEMICAL MATE (CN) 2009-04-08 CN claimed
CN-101130680-A Environment protection type single-component polyurethane binder, production and use method of the same SHANGDONG DONG DA INOV POLYUER (CN) 2008-02-27 CN claimed
CN-101096560-A Environment-friendly type polyurethane combined material and using method SHANGDONG DONG DA INOV POLYUER (CN) 2008-01-02 CN claimed
CN-1865324-A Low temperature resistant polyvinyl chloride salt film for anti-aging DONGYING TIANYUAN PLASTIC INDU (CN) 2006-11-22 CN claimed
US-6239197-B1 TO AN EXTENT SUCH THAT THE BULK DENSITY OF THE POLYMER ADDITIVE IS INCREASED AT LEAST 50% GREAT LAKES CHEMICAL CORPORATION 2001-05-29 US claimed
EP-0228996-A2 Antiflaking agent WARNER-LAMBERT COMPANY (US) 1987-07-15 EP claimed