SCHEMBL1758035

SCHEMBL1758035

Cc1ccc(C(=O)c2ccc(C)cc2O)c(O)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
TRPA1 O75762 2/20 0.54
CSNK2A1 P68400 1/20 0.54
TAS1R3 Q7RTX0 1/20 0.53
TAS1R1 Q7RTX1 1/20 0.53
TAS1R2 Q8TE23 1/20 0.53
IDO1 P14902 1/20 0.49
TDO2 P48775 1/20 0.49
PLG P00747 3/20 0.47
KLK1 P06870 2/20 0.47
KLK6 Q92876 2/20 0.47
LMNA P02545 3/20 0.47
HPGD P15428 2/20 0.47
CHRM1 P11229 2/20 0.47
SLC6A2 P23975 2/20 0.47
ADRA1A P35348 2/20 0.47
CYP1A2 P05177 1/20 0.47
PGR P06401 1/20 0.47
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30578000 1.00 NPC1 (0.56) NPC1RAB9ATRPA1CSNK2A1TAS1R3
SCHEMBL14274483 0.92 NPC1 (0.54) NPC1RAB9ATRPA1CSNK2A1TAS1R3
SCHEMBL11230455 0.92 CES2 (0.57) NPC1RAB9ACSNK2A1TAS1R3TAS1R1
SCHEMBL2167285 0.90 LMNA (0.62) NPC1RAB9ACSNK2A1IDO1TDO2
SCHEMBL29670690 0.88 HDAC1 (0.55) NPC1RAB9ATRPA1CSNK2A1TAS1R3
SCHEMBL351892 0.88 HDAC1 (0.55) NPC1RAB9ATRPA1CSNK2A1TAS1R3
SCHEMBL11350747 0.87 NPC1 (0.64) NPC1RAB9ATAS1R3TAS1R1TAS1R2
SCHEMBL12909853 0.87 ALDH1A1 (0.51) NPC1RAB9ATAS1R3TAS1R1TAS1R2
SCHEMBL12325927 0.85 ALDH1A1 (0.68) CSNK2A1IDO1TDO2LMNAHPGD
SCHEMBL12415231 0.85 NPC1 (0.83) NPC1RAB9ATAS1R3TAS1R1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146688-A 5D colorful stone-like paint and preparation method thereof 海南祥庭科技有限公司 2024-06-07 CN claimed
JP-4091274-A None JP disclosed
CN-118146688-A 5D colorful stone-like paint and preparation method thereof 海南祥庭科技有限公司 2024-06-07 CN disclosed
US-11873439-B2 Polymerisable liquid crystal material and polymerised liquid crystal film MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
US-20230311456-A1 DISPLAY DEVICE MEMBER, OPTICAL LAMINATE, AND DISPLAY DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2023-10-05 US disclosed
CN-107922347-A New imide derivative and its purposes as medicine 田边三菱制药株式会社 2018-04-17 CN disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
US-20160231606-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2016-08-11 US disclosed
US-9354356-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2016-05-31 US disclosed
US-9348177-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2016-05-24 US disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 US disclosed
US-20070048458-A1 Optical film, method of producing the same, optical compensatory film, polarizing film, and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-03-01 US disclosed
EP-1689495-B1 IMPROVED COSMETIC COMPOSITION COMPRISING VITAMIN B3, VITAMIN B6 AND AN ORGANIC ACID UNILEVER PLC (GB) 2007-02-28 EP disclosed
US-20070040962-A1 Optical resin film and polarizing plate and liquid crystal display using same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-22 US disclosed
US-20050100517-A1 synergistic skin lightening composition comprising: vitamin B6 or derivative, vitamin B3 or derivative, and C1-C16 monocarboxylic acid, dicarboxylic acid, polycarboxylic acid, phenolic acid, or an ester/salt; for treating freckles, hyper-pigmented or blotchy skin, melasmas, cholasmas, age spots, etc. UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2005-05-12 US disclosed
US-20040219115-A1 Cosmetic composition UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-11-04 US disclosed
US-20040077821-A1 Flame retarding resin composition CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-22 US disclosed
US-6258344-B1 WATER-IN-SILICONE GEL ENHANCES HYDROQUINONE DERIVATIVES SKIN PENETRATION EFFECT THE PROCTER & GAMBLE COMPANY 2001-07-10 US disclosed
JP-H0491274-A METHOD FOR TREATING FIBROUS MATERIAL NIKKA CHEM CO LTD 1992-03-24 JP disclosed
JP-H00491274-A 0001-01-01 JP disclosed